We report a 77-year-old man from Italy with a painful, red right eye with decreased vision (Figure 1A) and multiple asymptomatic erythematous infiltrated nodules and edematous plaques on the face (Figure 1B), tongue (Figure 1C), and trunk and extremities (Figure 1D). Lesions appeared on his face 20 years ago and progressively enlarged and diffused on the trunk. Two of his relatives had been aff...

Though testicular involvement is well known in leprosy, there are only few published reports on the presence of lesions of leprosy on male genital skin. In most of the cases reported, lesions were present on the scrotum with or without involvement of penile shaft, prepuce or glans. We report herein, a case of borderline lepromatous (BL) leprosy in type 1 reaction with cutaneous lesion over the ...

Leprosy is a chronic inflammatory disease caused by Mycobacterium leprae. The human response to this pathogen exhibits intriguing aspects which are up to now not well understood. The present study discusses the probable mechanisms involved in T cell-specific unresponsiveness observed in lepromatous patients. Analysis of the cytokine profile either in blood leukocytes or in skin specimens taken ...

Specimens of b one m arrow or liver were coHected from patien ts with lepromatous leprosy at the same time that skin biopsy specimens were removed . The viability of the bacilli was measured by inoculation into mice. There were 2 0 bone ·marrow specimens, and infectivity for mice was present in all of the 1 6 that came from patients whose skin specim ens contained bacill i infective for mice. T...

A cross-sectional clinical trial in which the serum anti-phenolic glycolipid (anti-PGL-1) antibodies were analysed in household contacts (HHC) of patients with leprosy as an adjunct early leprosy diagnostic marker was conducted. The families of 83 patients underwent clinical examination and serum anti-PGL1 measurement using enzyme-linked immunosorbent assay. Of 320 HHC, 98 were contacts of lepr...

Background and objectives High-resolution ultrasonography (HRUS) has become a vital imaging tool in the management of leprosy. This case-control study analyzed sonographic data on median nerves leprosy healthy controls to identify features characteristic Methods Newly diagnosed treatment naïve Hansen’s patients both sexes aged >16 years were included study. The control group prospectively en...