نتایج جستجو برای: i gene
تعداد نتایج: 2077523 فیلتر نتایج به سال:
Background and Objectives: The neuromuscular degenerative disorder, known as spinal muscular atrophy (SMA), is a common fatal disease in neonates. In most patients with SMA, exon 7 and/or exon 8 of SMN1 gene is deleted. It is reported that the deletion of exon 5 from NAIP gene may be involved in the severity of SMA disease. The present study was aimed to evaluate the genotype- phenotype correla...
Background: Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world and is characterized by progressive degeneration of the retinal pigment epithelium and secondary photoreceptor loss, resulting in visual loss. Etiological research suggests that age related macular degeneration is a complex disease, caused by the interactions of several genetic and enviro...
Background and Aims: lamivudine is amongst the antiviral for drug chronic hepatitis B treatment. During therapy with lamivudine, variants may emerge with YMDD mutation in the reverse transcriptase (RT) region of polymerase gene. This mutation might have a role in drug resistant for HBV. Materials and Methods: HBV DNA extraction from serum sample of 88 patients, were subjected to nested PCR for ...
Background: Avian infectious bronchitis (IB), with avianinfectious bronchitis virus (IBV) as the causing agent, is a ubiquitous endemicdisease of the chicken with devastating effects on its industry. A viralmembrane surface protein called S notonly induces neutralizing antibodies but also plays an important role in virusbinding and entry to host cells. Technically, S1 protein gene sequencing a...
چکیده: انگلهای تک یاخته جنس لیشمانیا طیف وسیعی از عفونت ها را با شدت بیماریزایی متفاوت در انسان ایجاد می کنند که از زخمهای پوستی بهبود یافته تا بیماریهای احشایی بسیار شدید را در بر می گیرد. علی رغم تلاشهای بسیار هنوز کنترل بیماری میسر نگردیده است. در تمام سلولهای زنده اعم از سلولهای پروکاریوت و یوکاریوت پروتئینهای ترشحی معمولاً بصورت پروتئینهای پیش ساز که دارای یک توالی پپتید نشانه در انتهای ...
background: we aimed to elucidate the association between fat mass and obesity associated gene (fto) polymorphism and the risk of polycystic ovary syndrome (pcos) by meta-analysis. methods: we searched pubmed and embase databases to find the relevant studies. odds ratios (ors) and their corresponding 95% confidence intervals (cis) were used for pooled analysis. statistical analyses were carried...
background attention deficit hyperactivity disorder (adhd) is a multi-factorial disorder that has defined by hyperactivity, impulsivity and attention deficits. various neurotransmitters such as dopamine can play a role in its pathophysiology. the aim of this study was to examine the association of two common single nucleotide polymorphisms in drd2 gene, taq i a (t/c) and taq i b (g/a), with adh...
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