Since 1938, nine cases of nasopharyngeal involvement by craniopharyngioma have been described in the medical literature (1–3). Six of these cases involved the sella turcica, and all but one (1) extensively involved the sphenoid sinus. We report a case of a nasopharyngeal craniopharyngioma sparing the sella turcica. The tumor is thought to have likely arisen from the pharyngeal hypophysis. Magne...

Pituitary gland is an uncommon site of metastasis for malignancies. However, breast cancer is the most common primary metastasizing to hypophysis in women. It may cause hormonal problems in different patterns due to mass affect and invasion to pituitary gland. We present a 53-year-old woman with HER-2 positive breast cancer presenting with intermittent symptoms of diabetes insipidus and rapidly...

Anaplastic large T-cell lymphoma (ALCL) is frequently associated with the t(2;5)(p23;q35). Here, we report a case of ALCL with an atypical translocation of t(2;5)(p24;q13) and other complex translocations. This complex abnormal karyotype may result in chemotherapy resistance and a poor outcome. Interestingly, a hypophyseal tumor was detected simultaneously by magnetic resonance imaging in this ...

Zinc has been located using both histochemical and autoradiographic procedures in the neurons of the nuclei of the hypothalamic medial area and in some adenohypophisary cells. Some suggestions about the functional significance of the presence of Zn in these places are made.

Hypophysectomized or sham-operated male rats were exposed to hypoxia (0.42--0.40 or 0.37--0.35 atm for 6, 12, or 24 hr) applied 2 wk to 7 mo after surgery. Erythropoietin (Ep) levels in rat serum were evaluated on the basis of the exhypoxic polycythemic mouse assay. Ep activity evoked by hypoxia was significantly lower in hypophysectomized rats than in sham-operated controls. Progressive increa...

For a number of years the anterior hypophysis has been known to play an important r61e in the regulation of body growth. I n general, the effects of hypophyseal secretions on growth have been found to be of a stimulative character. The growth stimulating or inhibiting action of such hormones is demonstrated most precisely by the changes they elicit in those tissues which normally undergo the mo...