Tramadol misuse can lead to severe intoxication in which respiratory failure and seizures are frequent. We reviewed 7 paediatric cases of patients hospitalized in the Intensive Care Unit. We reported unusual hypertonia and chest rigidity leading to ventilator difficulties. None of the children were suspected to be ultra-rapid metabolizers, and one case led to death. Overdoses can lead to death ...

An 11-month-old girl presented with episodic severe stridor from birth, often resulting in cyanosis. Her parents had noted recurrent unilateral ptosis. Later she developed spasms of her hands during exercise. Psychomotor development was normal. Neurologic examination showed generalized hypertonia. Cerebral MRI excluded a Chiari malformation. Laryngoscopy under general anesthesia showed no abnor...

A 68-year-old fell walker, at the end of a 20 miles walk taking 12 h, noticed the progressive onset over several minutes of an irresistible lean to the left forcing him to rest before carrying on to his destination (Figure 1). The symptoms worsened and were provoked by shorter distances over the next 6 months. He had no other serious illnesses other than wellcontrolled hypertension. He displaye...

A 32 years female presented with gradually progressive dysarthria, dysphagia, oromandibular dystonia and mild generalized weakness. She had several episodes of acute psychotic behavior. She had abnormal saccadic eye movements, generalized hypertonia and exaggerated jerks in upper limbs. She was previously treated in a peripheral hospital for severe vomiting and diarrhea. MRI of brain revealed s...

Mesobuthus martensii Karsch, commonly known as the Chinese scorpion or Manchurian scorpion, has been used in traditional Chinese medicine as Quanxie to treat chronic pain, tetanus, tremors, convulsion, and paralysis for more than a thousand years. We report a case of poisoning after ingestion of a teaspoon of Quanxie powder. The patient presented with chest pain, dizziness, diaphoresis, general...

Spast ic i ty is def ined as a movement disorder characterised by a velocity-dependent increase in tonic stretch reflexes. Children with spastic CP have a neuromuscular mobility impairment stemming from an upper motor neuron lesion in the brain over the areas in the motor cortex or the corticospinal tract, which descends in the spinal cord, in the lateral columns and carries signals for volunta...

An 8 year old boy with ring chromosome 21 who was susceptible to sinorespiratory infections due to hypogammaglobulinaemia is reported. He presented with the characteristic features of monosomy 21 syndrome, such as psychomotor retardation, hypertonia, large saccular ears, prominent nasal bridge, micrognathia, thrombocytopenia, and patent ductus arteriosus. His serum IgG concentration was less th...

Introduction : Spastic hypertonia (SH) is a motor disorder characterized by exaggerated tendon jerk reflexes, and is a common symptom associated with spinal cord injuries. Current assessment methods for SH rely on subjective examination. We utilize an inexpensive and lightweight handgrip device, previously designed by the authors, to objectively quantify SH in patients with cervical spondylotic...

We describe a case of neuro-Behçet disease diagnosed in a 12-year-old girl. This patient presented with recurrent oral ulcers, incontinence, spastic gait, blurry vision, and asymmetrical lower extremity hypertonia. Extensive testing revealed punctate lesions through the central nervous system, vitritis, papillitis, and uveitis. A thorough infectious and neoplastic workup was negative. She was t...