نتایج جستجو برای: hyperphagia
تعداد نتایج: 1289 فیلتر نتایج به سال:
In order to determine the r61e played by the central nervous system in regulating blood meal size, the ventral nerve cord was cut at various sites along its length in the female mosquito, Aedes aegypti. When the cord was cut anterior to the second abdominal ganglion, massive hyperphagia resulted, many females ruptured, and blood intake was more than four times that of the untreated controls. As...
Anti-Ma2 encephalitis is a rare form of autoimmune that has classically been described as paraneoplastic neurobehavioral disorder due to its association with underlying malignancies. We discuss the case 30-year-old female an exceptionally aggressive presentation anti-Ma2 accompanied by Klüver-Bucy syndrome and hypothalamic dysfunction. Her course was complicated repeated aspiration events secon...
1. Bipiperidyl mustard produced increased adiposity in the rat without excessive weight gain or hyperphagia. 2. The results suggest a metabolic aetiology for the obesity as opposed to a disorder of food intake regulation.
Experimental study of hypothalamic obesity is based upon a foundation laid by clinicians who described lesions of the hypophysiohypothalamic region in obese human patients. Because of the non-specific character of the lesions which they found, previous investigation was naturally directed toward discovering whether damage to the hypothalamus, to the hypophysis, or to both was necessary to produ...
The cJun NH2-terminal kinase (JNK) signaling pathway is implicated in the response to metabolic stress. Indeed, it is established that the ubiquitously expressed JNK1 and JNK2 isoforms regulate energy expenditure and insulin resistance. However, the role of the neuron-specific isoform JNK3 is unclear. Here we demonstrate that JNK3 deficiency causes hyperphagia selectively in high fat diet (HFD)...
Skeletal muscle insulin resistance is a predictor of the development of type 2 diabetes and maintenance of adequate muscle glucose disposal in muscle may help to prevent diabetes. Lipodystrophy is a type of diabetes caused by a reduction of white adipose tissue and the adipokine leptin. Lipidemia, insulin resistance and hyperphagia develop as a consequence. In a recent study, we showed that inc...
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