نتایج جستجو برای: hypericum perforatum 6 hydroxydopamine rotational behavior motor imbalance dose dependent

تعداد نتایج: 2491149  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2011
Riccardo Viaro Michele Morari Gianfranco Franchi

Many studies have attempted to correlate changes of motor cortex activity with progression of Parkinson's disease, although results have been controversial. In the present study we used intracortical microstimulation (ICMS) combined with behavioral testing in 6-hydroxydopamine hemilesioned rats to evaluate the impact of dopamine depletion on movement representations in primary motor cortex (M1)...

2018
Shih-Chang Hsueh Kai-Yun Chen Jing-Huei Lai Chung-Che Wu Yu-Wen Yu Yu Luo Tsung-Hsun Hsieh Yung-Hsiao Chiang

BACKGROUND Parkinson's disease (PD) is typically characterized by impairment of motor function. Gait disturbances similar to those observed in patients with PD can be observed in animals after injection of neurotoxin 6-hydroxydopamine (6-OHDA) to induce unilateral nigrostriatal dopamine depletion. Exercise has been shown to be a promising non-pharmacological approach to reduce the risk of neuro...

Journal: :GSC biological and pharmaceutical sciences 2023

In this study, histopathological and immunohistochemical evaluations were made on the damage to gastric tissue in peptic ulcer model induced by indomethacin, it was investigated whether plants Hypericum perforatum Rosa spinosissima have a therapeutic effect. order create an model, 25mg/kg indomethacin administered orally rats other groups, except sham control group, 2 doses, 24 hours apart. tre...

Mehrdad Roghani, Tourandokht Baluchnejadmojarad,

ABSTRACTParkinson’s disease (PD) is a neuropathological and debilitating disorder involving the degeneration of mesencephalic dopaminergic neurons. Neuroprotective effect of hesperetin has already been reported, therefore, this study examined whether the administration of this flavonoid would attenuate behavioral abnormalities in an experimental model of PD in rat. For this purpose, unilateral ...

Journal: :Complementary Medicine Research 1999

2010
JOHN E. WALSH John E. Walsh Norman A. Phillips

ACKNOWLEDGEMENTS TABLE OF CONTENTS LIST OF FIGURES LIST OF TABLES

2002
Robert M. Colomb

This paper argues that the physical being of one of John Searle's institutional facts is the totality of records of the fact, together with some very specific background activities and capacities. Abstract: This paper argues that the physical being of one of John Searle's institutional facts is the totality of records of the fact, together with some very specific background activities and capac...

Journal: :The Journal of the Indiana State Medical Association 1960
M WILSON

2014
Jelena Stamenković Ivana Radojković Aleksandra Đorđević Olga Jovanović Goran Petrović Gordana Stojanović

Stamenković, J., Radojković, I., Đorđević, A., Jovanović, O., Petrović, G., Stojanović, G.: Optimization of HPLC method for the isolation of Hypericum perforatum L. methanol extract. Biologica Nyssana, 4 (12), December 2013: 81-85. St. John's Wort (Hypericum perforatum L.) is one of the most studied plant species in the family Hypericaceae. The aim of this study was the identification of the co...

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