The effect of hyoscine butylbromide (scopolamine butylbromide), a competitive nonselective antagonist of acetylcholine at muscarinic receptors, on the isolated rabbit duodenum, ileum and colon was investigated. Hyoscine butylbromide (9×10M 9×10M) decreased in a concentration-dependent manner the amplitude of the spontaneous pendular movements of the rabbi-isolated duodenum (r=0.99; p<0.001), il...

Cross benzoin condensation using room temperature ionic liquids, namely 1-butyl-3-methylimidazolium bromide ([Bmim][Br]), acted as catalyzed and a solvent under NaOH base condition to afford desired cross-benzoin products 4a-i in satistactory yields (60-70%.) Homo-benzoin 5a-d 6a also were occurred side reactions 9-18% yields.

A simple, novel, efficient and three-component procedure for the synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives by the reaction of 6-amino-1,3-dimethyluracil, aldehyde and 2-benzylisothiourea hydrochloride promoted by ionic liquid 1-butyl-3-methylimidazolium bromide ([BMIm]Br) under solvent-free conditions is reported. The presented method is benefited from operational simplicity...

Purpose: Oculocardiac reflex (OCR) is a frequent event during strabismus surgery. The aim of this study is to compare the preventive effect of intravenous lidocaine and hyoscine on OCR. Methods: This prospective, randomized clinical trial was performed on 75 patients (5-63 years old) underwent strabismus surgery. Patients divided randomly into three groups. Intravenous hyoscine (0.2 mg/kg), lid...

OBJECTIVES: The removal of pre-malignant colorectal lesions prevents cancer. Hyoscine has been proposed as a means of improving diagnosis by reducing colonic movements. The aim of this study was to analyze whether this anti-spasmodic enhances the detection of pre-malignant colorectal lesions. METHODS: In a randomized, double-blinded fashion patients received hyoscine or a saline solution in a...

A simple, novel, efficient and three-component procedure for the synthesis of pyrimido[4,5-d]pyrimidine-2,4-dione derivatives by the reaction of 6-amino-1,3-dimethyluracil, aldehyde and 2-benzylisothiourea hydrochloride promoted by ionic liquid 1-butyl-3-methylimidazolium bromide ([BMIm]Br) under solvent-free conditions is reported. The presented method is benefited from operational simplicity...

Objective: Hyoscine-N-butylbromide is used by some surgeons during laparoscopic sleeve gastrectomy (LSG) to loosen gastric smooth muscles and provide a more effective LSG. However, evidence-based data on the effects of hyoscine-N-butylbromide in are limited its effect surgery weight loss unknown. The aim this study was analyze intraoperatively administered stomach resection volume, complication...