background: the spice zingiber officinale or ginger possesses antioxidant activity and neuroprotective effects. in this study we hypothesized that treatment with hydroethanolic extract of ginger (50, 100 and 200 mg/kg, p.o) would effect on the hyoscine-induced memory impairment in rats. methods: in this experimental study 64 male wistar rats were divided into eight groups (8 rats in each group)...

years ago. He gave a history of two attacks of what appeared to me to be appendicitis, though the pain was all on the left side. The abdomen appeared rather small, but I thought it would contain the contents of the sac when reduced. I admitted him to my nursing home and gave him careful preparation for three days. On December 15th, I gave him an injection of i gr. morphia and hyoscine gr. ^ + a...

BACKGROUND Patients with acute renal colic usually require immediate diagnosis and treatment. In this clinical trial analgesic effect of hyoscine N-butyl bromide and desmopressin combination in comparison with hyoscine N-butyl bromide alone in patients with acute renal colic induced by urinary stones was assessed. METHODS The study included 114 patients randomly allocated in two groups (A and...

BACKGROUND AND AIM Postoperative catheter-related bladder discomfort (CRBD) can be a distressing complication for patients in whom a urinary catheter was inserted intraoperatively and is accompanied with patients' dissatisfaction. This trial investigated the efficacy of hyoscine and ketamine on treatment of postoperative CRBD in patients undergoing various surgeries. MATERIAL AND METHODS This...

OBJECTIVE Investigate whether hyoscine patch or glycopyrronium liquid is more effective and acceptable to treat drooling in children with neurodisability. DESIGN Multicentre, single-blind, randomised controlled trial. SETTING Recruitment through neurodisability teams; treatment by parents. PARTICIPANTS Ninety children with neurodisability who had never received medication for drooling (55...

Objective(s): Crocus sativus L. and its active constituent, crocin, have neuroprotective effects. The effects of crocin on memory impairment have been mentioned in studies but the signaling pathways  have not been evaluated. Therefore, the aim of this study was to evaluate the effects of crocin on the hyoscine-induced memory impairment in rat. Additionally, the level o...

  In order to determine prevalence of Echinoccocus and other intestinal helminths infection one hundred stray dogs were examined in Mashhad area, Khorasan province of Iran. Helminths were collected from intestinal contents obtained at the time necropsy. Ninety one percent of the dogs were infected by different helminths. The prevalence of Echinococcus granulosus was (22%). Eighteen (81%) of inf...

AIMS Hyoscine (scopolamine), which is effective in the prophylaxis of motion sickness, shows similar binding affinities to all of the five known muscarinic receptor sub-types. The effectiveness of hyoscine was compared with zamifenacin (UK-76654), which binds selectively to the muscarinic M3 and m5 receptors. METHODS Eighteen subjects received hyoscine hydrobromide 0.6 mg, zamifenacin 20 mg, ...