نتایج جستجو برای: hynic

تعداد نتایج: 217  

Abbas Shafiee Gholamali Shabani Mohammad Hossein Babaei Mohannad Rabbani Mostafa Gandomkar Reza Najafi Seyed Esmail Sadatebrahimi

Somatostatin analoges labeled with different radionuclides are able used for imaging and treatment of somatostatin receptor positive tumors. In this study Tyr³-Octreotide protected at lysine as an analoge of somatostatin was conjugated with bifunctional chelating agent 6-BOC-hydrazinopyridine-3-carboxylic acid (BOC-HYNIC) and after deprotecting of conjugate, purification was performed wit...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008
Ming Zhao Zhixin Li Scott Bugenhagen

UNLABELLED With only 19 amino acids, duramycin is the smallest known polypeptide that has a defined 3-dimensional binding structure. Duramycin binds phosphatidylethanolamine (PtdE) at a 1:1 ratio with high affinity and exclusive specificity. As an abundant binding target, PtdE is a major phospholipid and accounts for about 20% of the phospholipid content in mammalian cellular membranes. PtdE is...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014
Yanye Lu Kun Yang Kedi Zhou Bo Pang Guohe Wang Yichen Ding Qiushi Zhang Hongbin Han Jiahe Tian Changhui Li Qiushi Ren

UNLABELLED We developed a novel integrated quad-modality system that included 3 molecular imaging methods (PET, SPECT, and fluorescence molecular imaging [FMI]) and 1 anatomic imaging modality (CT). This system could study various biologic processes in the same animal using multiple molecular tracers. In addition to the technology development, we also discussed the optimization strategy of the ...

2010
Meser M. Ali Branislava Janic Abbas Babajani-Feremi Nadimpalli R. S. Varma A. S. M. Iskander John Anagli Ali S. Arbab

BACKGROUND Anti-angiogenic treatments of malignant tumors targeting vascular endothelial growth factor receptors (VEGFR) tyrosine kinase are being used in different early stages of clinical trials. Very recently, VEGFR tyrosine kinase inhibitor (Vetanalib, PTK787) was used in glioma patient in conjunction with chemotherapy and radiotherapy. However, changes in the tumor size, tumor vascular per...

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