[reaction: see text] Responsive amphiphilic molecular baskets were obtained by attaching four facially amphiphilic cholate groups to a tetraaminocalixarene scaffold. Their binding properties can be switched by solvent changes. In nonpolar solvents, the molecules utilize the hydrophilic faces of the cholates to bind hydrophilic molecules such as glucose derivatives. In polar solvents, the molecu...

5-Thiourea and 5-dithiocarbamate oxazolidinones were synthesized as a continuation of research on 5-thiocarbonyl oxazolidinone antibacterial agents considering the hydrophobic parameters of the molecule. The structure-activity relationship (SAR) study revealed that the antibacterial activity on 5-thiocarbonyl oxazolidinones was significantly affected by the lipophilicity, especially the calcula...

This paper presents the principle, fabricated structure, characterization and results obtained for a new class of surfaces—“hydrophobic non-fouling surfaces”—for droplet-based microfluidics. Building on the theory of wetting of rough surfaces, we have developed novel surfaces which are chemically hydrophilic, i.e., the droplet is in contact with a non-fouling hydrophilic material but exhibits h...

Single atomic monolayer (SAM) technology will be used to design an air bubble array for the lubrication of MEMS devices with sliding and rotating parts. Patterning a matrix of hydrophobic patches on a hydrophilic substrate will result in an array of air bubbles formed by the repulsive behavior of water molecules with the hydrophobic surfaces. The performance of the air bubble array will be dete...

Paper-based microfluidic devices are emerging as a new technology for simple, low-cost, portable, and disposable diagnostic and monitoring platform. This article presents a novel method for fabricating microfluidic devices on paper by means of octadecyltrichlorosilane self-assembling and UV/O3-patterning. The hydrophilic filter paper was uniformly coated with a hydrophobic layer of octadecyltri...

A method for determining the rate of hydrophilic and hydrophobic drugs release from different types of liposomal dispersions and gels using a dialysis method is described. Dibucaine base and 5-fluorouracil were used as model drugs for a hydrophobic and a hydrophilic drug, respectively. A dialysis technique was employed. Release rates were affected by the rate of rotation of the paddles of the t...

Two new surfactant molecules are reported that contain thermally labile Diels-Alder adducts connecting the hydrophilic and hydrophobic sections of each molecule. The two surfactants possess identical hydrophobic dodecyl tail segments but have phenol and carboxylic acid hydrophilic headgroups, respectively. Deprotonation with potassium hydroxide affords the formation of water-soluble surfactants...