The clinical development of neuropeptides has been limited by a combination of the short plasma half-life of these drugs and their ultimate failure to permeate the blood brain barrier. Peptide nanofibres have been used to deliver peptides across the blood brain barrier and in this work we demonstrate that the polymer coating of peptide nanofibres further enhances peptide delivery to the brain v...

The application of a coating layer on a tablet is a commonly used technique to selectively control tablet characteristics. Among the most important functions of the coating is the regulation of the release of active ingredient. In the course of a typical coating process, the tablet passes a spray zone multiple times. Each time, a partial coating layer is applied. For each tablet, this is repeat...

The protective performance of a sand particle-modified enamel coating on reinforcing steel bars was evaluated in 3.5 wt% NaCl solution by electrochemical impedance spectroscopy (EIS). Seven percentages of sand particles by weight were investigated: 0%, 5%, 10%, 20%, 30%, 50% and 70%. The phase composition of the enamel coating and sand particles were determined with the X-ray diffraction (XRD) ...

“Stickies” are tacky species, present in recycled paper and coated broke, derived from coating formulations, adhesives etc. They impact negatively on paper quality and cause web runnability problems by deposit build-up. To sustain recycling, stickies are controlled by adsorbing them onto minerals added to the recycled stock. We report isotherms for a fatty acid ester defoamer and an acrylic aci...

PURPOSE Magnetic submicron particles (MSPs) are pivotal biomaterials for magnetic separations in bioanalyses, but their preparation remains a technical challenge. In this report, a facile one-step coating approach to MSPs suitable for magnetic separations was investigated. METHODS Polyethylene glycol) (PEG) was derived into PEG-bis-(maleic monoester) and maleic monoester-PEG-succinic monoeste...

Regenerative cooling using hydrocarbon fuel requires thermal decomposition to increase heat absorption, but a high temperature is required initiate and catalysis expected enhance at lower regime. The effects of on coking normal-dodecane methyl-cyclo-hexane within tube heater were experimentally investigated. Platinum (Pt) was spread the inner surface stainless tube, heated target values an elec...

The coating quality of a batch of lab-scale, sustained-release coated tablets was analysed by terahertz pulsed imaging (TPI). Terahertz radiation (2 to 120 cm(-1)) is particularly interesting for coating analysis as it has the capability to penetrate through most pharmaceutical excipients, and hence allows non-destructive coating analysis. Terahertz pulsed spectroscopy (TPS) was employed for th...

Major joining methods of dental casting metal include brazing and laser welding. However, brazing cannot be applied for electroformed metals since heat treatment could affect the fit, and, therefore, laser welding is used for such metals. New methods of joining metals that do not impair the characteristics of electroformed metals should be developed. When new coating is performed on the surface...