EPI with Keyhole (EPIK) is a hybrid imaging technique used to improve the performance of EPI in dynamic MRI applications. The method had been previously validated at 1.5 T with both phantom and in vivo images; EPIK was able to provide a higher temporal resolution and less image distortions than single-shot EPI. The data presented here demonstrate that the performance of EPIK can be further impr...

The relentless progress that is being made in tomographic imaging modalities is inexorably expanding the application of positron emission tomography (PET) in the clinical field. Some of the most noteworthy advances involve innovations in quantitative techniques for hybrid imaging modalities such as PET/Computed Tomography (CT) and PET/Magnetic Resonance Imaging (MRI), which have greatly improve...

m c Combined evaluation of coronary anatomy and myocardial ischemia has become the holy grail of noninvasive diagnostic imaging. Several approaches, such as hybrid imaging combining coronary computed tomography angiography (CTA) for anatomy and stress-rest nuclear imaging for perfusion, are adding to the complexity, cost, and radiation burden of both techniques. In theory, a single imaging devi...

Cardiovascular imaging has largely focused on identifying structural, functional, and metabolic changes in the heart. The ability to reliably assess disease activity would have major potential clinical advantages, including the identification of early disease, differentiating active from stable conditions, and monitoring disease progression or response to therapy. Positron emission tomography (...

Following PET/CT and SPECT/CT, PET/MR hybrid imaging is the most recent addition to the palette of hybrid cardiac imaging modalities. PET/MR synergistically combines the excellent soft tissue contrast and detailed image resolution of MR with metabolic information provided by PET. Integrated PET/MR systems furthermore offer the ability to acquire hybrid imaging data simultaneously (1). Beyond ex...

Photoacoustic (PA) imaging is a hybrid biomedical imaging method that exploits both acoustical Epub ahead of print and optical properties and can provide both functional and structural information. Therefore, PA imaging can complement other imaging methods, such as ultrasound imaging, fluorescence imaging, optical coherence tomography, and multi-photon microscopy. This article reviews technique...

Noninvasive imaging of atherosclerosis could potentially move patient management towards individualized triage, treatment, and followup. The newly introduced combined positron emission tomography (PET) and magnetic resonance imaging (MRI) system could emerge as a key player in this context. Both PET and MRI have previously been used for imaging plaque morphology and function: however, the combi...

Herein, we fabricated efficient MR imaging probes by incorporating gadolinium oxide nanoparticles (Gd2O3) and gadolinium hybrid nanoparticles (GH) within RBCs. The Gd2O3 and GH encapsulated in the RBCs exhibited high relaxation rates and revealed high sensitivity for T1 MR imaging.