At the NCCN 2023 Annual Conference, experts reviewed clinical data on established therapies for patients with metastatic renal cell carcinoma and discussed strategies to effectively manage both clear non–clear tumor histologies in setting of advanced stages. Depicted through 3 separate case studies, they strategized selection optimal first-line subsequent-line based individual study characteris...

background and aims: p504s (amacr) is a mitochondrial enzyme expressed in renal cell carcinoma. some of immunohistochemical markers in renal cell tumors are independent prognostic factor and show relation with histologic grading. amacr expression increases with higher histological grading in different tumors; however, in rcc it is not obvious. in this study, we tried to investigate if any relat...