Background: Herpes simplex virus type 2 (HSV-2) is a common infection in human immunodeficiency virus (HIV) patients and may accelerate HIV progression by rising HIV viral load and decreasing CD4 count. However, the available data regarding the influence of HSV-2 seropositivity on HIV progression in HIV individuals are inconclusive. Therefore, we aimed to determine HSV-2 seroprevalence in na&iu...

Macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains are able to grow to high titers in human monocyte-derived macrophages. However, it was recently reported that cellular protein SAMHD1 restricts HIV-1 replication in human cells of the myeloid lineage, including monocyte-derived macrophages. Here we show that degradation of SAMHD1 in monocyte-derived macrophages was associated...

The human immunodeficiency virus (HIV) since its genesis has continued to affect a large number of the population in African region and caused exponential deaths. At same time, new infections have been reported South Africa. However, religion as vehicle change through institution church acting on contrary, it discourages use condoms (one most effective ways prevent HIV) moralising pelvic area c...

Human immunodeficiency virus (HIV) is a member of the Retroviridae (retrovirus) family. It associated with immunodeficiency, neurological diseases and neoplasms. With use antiretroviral therapy (ART), prognosis people who are infected HIV has improved, incidence HIV-related central nervous system (CNS) markedly decreased. In spite that mortality from CNS remains significant. Magnetic resonance ...

Human herpes virus-8 (HHV-8), now called Kaposi’s sarcoma-associated herpes virus (KSHV), as a probable causative agent of Kaposi’s sarcoma (KS) was putforth when it was first detected in KS specimens in 1994. Since then, many investigators have confirmed the association of HHV-8 and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) associated KS. This study was done ...

Each year, millions of children are born with human immunodeficiency virus (HIV), a quarter whom adhere poorly to HIV treatment guidelines. This study uses simple mathematical model investigate the basic dynamic processes by which infected newborns under progress AIDS and contribute its spread. The results indicate that disease-free steady state is unstable, raising substantial concern from pub...

Background: Unsafe transfusion practices put patients at high risk of transfusion transmissible infections. We aimed to evaluate the prevalence of transfusion transmissible infections (including Human Immunodeficiency Virus [HIV] 1 and 2, Hepatitis B Virus [HBV], Hepatitis C Virus (HCV) and syphilis) during a period of 18 months among blood donors in the Blood Bank of Lady Hardinge Medical Coll...

Background: In patients who are hepatitis B virus (HBV) DNA-positive, but HBV surface antigen (HBsAg) -negative, the infection is referred to as occult hepatitis B infection (OBI). Occult HBV infection is harmful when other liver diseases are present, and can aggravate liver damage in in patients with chronic liver diseases. In human immunodeficiency virus (HIV) infection the suppression of vir...

The recent outbreak of COVID-19 is considered to be one of the biggest disasters faced in the history which has already killed 211568 and effected 3065739 people across the world (As on 28th April 2020). Thus, there is an alarming need to discuss novel treatment strategies for treatment of such viral outbreaks. Viral diseases affect millions of people around the world, with a major effect on hu...

AIDS is an acquired immunodeficiency syndrome caused by the HIV virus (1, 2). AIDS is amongst the major challenges of the health system in all countries. This health challenge has spread to all countries as well as to all age groups, especially the 25-34 age group. The probability of transmission of AIDS ranges from 70% by blood transfusion to 30% by sexual intercourse, mother-to-child transmis...