نتایج جستجو برای: human immunodeficiency virus 1

تعداد نتایج: 4210208  

2013
Anfumbom KW Kfutwah Valerie Ngono Paul Alain Ngoupo Richard Njouom

INTRODUCTION Replication of the human immunodeficiency virus involves an obligatory step of reverse transcription of the viral ribonucleic acid genome into a double-stranded deoxyribonucleic acid, and subsequent integration of the deoxyribonucleic acid into the human chromatin to form the proviral deoxyribonucleic acid. This proviral human immunodeficiency virus deoxyribonucleic acid is a criti...

Journal: :Antimicrobial agents and chemotherapy 1989
R Koshida L Vrang G Gilljam J Harmenberg B Oberg B Wahren

We describe a synergistic effect of combinations of foscarnet and 3'-azido-3'-deoxythymidine against human immunodeficiency virus type 1 multiplication in cell culture, an additive effect of foscarnet and 3'-azido-3'-deoxythymidine triphosphate against human immunodeficiency virus type 1 reverse transcriptase, and a low toxicity in cell culture of combinations of the two drugs.

Journal: :Journal of virology 1989
M Niedrig J Hinkula W Weigelt J L'age-Stehr G Pauli J Rosen B Wahren

Murine monoclonal antibodies directed against the structural proteins p17 and p24 of human immunodeficiency virus type 1 were investigated in an epitope mapping system. Overlapping peptides consisting of 15 amino acids of the p17 and p24 protein, respectively, were used as competitors in an enzyme-linked immunosorbent assay. Three different immunogenic regions (A, B, and C) could be defined, on...

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