herpes simplex virus (hsv) causes a wide range of pathologies in the human central nervous system (cns) such as stroke. it was proposed that there is an association between hsv infection and stroke with different results reported by the researchers using different methods. this study aimed to investigate the frequency of hsv among stroke patient and control groups. we detected hsv in 28 stroke ...

conclusions: prevalence of hsv1/2 in mucocutaneous biopsies from pemphigus patients is 2.5% and possibly hsv1/2 has no role in the pathogenesis of pemphigus lesions. but resistant cases to treatment might be suspected to hsv. results: ten patients (25%) had a history of orolabial herpes infection. the results of all samples were negative for hsv1 except one sample which showed the positive resu...

Digestion of herpes simplex virus DNA by the HinIII or Eco RI restriction endonucleases yielded 11 to 15 fragments with molecular weights between 1 x 10(6) and 28 x10(6). The electrophoretic profiles obtained in 0.3% agarose gels with DNA fragments from none different strains of herpes simplex virus type 1 could be readily differentiated from the patterns exhibited by the corresponding fragment...

A series of twelve recently synthesized 6-substituted derivatives of 9-beta-d-ribofuranosylpurine 3',5'-cyclic phosphate (RPcMP) were evaluated for in vitro antiviral activity, using inhibition of viral cytopathogenic effect as the primary parameter for evaluation. Inhibition of the development of intra- and extracellular virus titer was used as a secondary criterion with certain viruses. Five ...

Sera from normal subjects were examined for reactivity to human herpesvirus 6 (HHV-6) by the anticomplement immunofluorescence test. Of a total of 179 serum specimens from donors aged from under 10 to 59 years, 141 specimens showed positive reactivity against HHV-6. The positive rate was 70 to 83% for all age groups, and there were no substantial differences in the positive rates. Sera from you...

BACKGROUND/AIM The aim of this study was to investigate the etiological role of human papilloma virus (HPV), herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6 (HHV-6) and -7 (HHV-7) in the occurrence of nasal polyposis. MATERIALS AND METHODS Nasal polyp samples from 30 patients with nasal polyposis and normal na...

During 2 consecutive influenza seasons we investigated the presence of influenza virus, human herpesvirus (HHV) type 6, and HHV-7 in cerebrospinal fluid samples from 9 white children suffering from influenza-associated encephalopathy. We conclude that it is unlikely that neuroinvasion by influenza virus or reactivation of either HHV-6 or HHV-7 is involved.