objective herpes simplex virus (hsv) infection during pregnancy may lead to fetal loss. the aim of this study was to explore the infection rate of hsv type 1 and 2 infection associated with spontaneous abortion in a pilot case-control study in two cities of iran in 2010. patients and methods placenta and curettage samples from 35 healthy full term neonates and 35 cases of spontaneous abortion w...

background herpes simplex virus type 1 and type 2 (hsv-1 and hsv-2) are common infectious agents worldwide. data on prevalence of hsv-1 and hsv-2 infections are limited in asia, especially in iran. our study aimed on determination of seroepidemiology of hsv-1 and hsv-2 infections in asymptomatic healthy students of islamic azad university of kazeroun, fars province, southwest of iran. patients ...

A longitudinal cohort research was conducted to see if gynaecological disorders besides the human papillomavirus (HPV) remain associated elevated threat cervical neoplasia. The included many women who participated in planned mass screening. Trichomonas vaginalis and HPV, respectively, remained linked through a significant comparative probability of preinvasive lesions, cancer invasive merged, l...

The replication of herpes simplex virus type I and herpes simplex virus type 2 was studied in two isolated hamster cell lines. These lines developed after being treated with herpes simplex virus type 2 inactivated with 7,~2-dimethylbenz(a)anthracene. One cell line that developed, HDC-22, had a hypodiploid chromosome number and was missing a D-group chromosome. Growth studies revealed that this ...

BACKGROUND Herpes simplex virus (HSV) is a major cause of genital ulcer disease worldwide and a significant factor for increased risk of acquisition and transmission of the Human Immune Deficiency Virus (HIV). The determination of the level of knowledge of genital herpes is necessary for the design and implementation of its specific preventive strategies as well as the reduction of the contribu...

Several sulfated polysaccharides (dextran sulfate, pentosan polysulfate, fucoidan, and carrageenans) proved to be potent inhibitors for herpes simplex virus, human cytomegalovirus, vesicular stomatitis virus, Sindbis virus, and human immunodeficiency virus. They were moderately inhibitory to vaccinia virus but not inhibitory to adenovirus, coxsackievirus, poliovirus, parainfluenza virus, and re...

Inhibitors of cell enzyme Inosine 5 ́-Monophosphate (IMP) dehydrogenase – Ribavirine (Rbv), Micophenolic acid (MPA) and Mizoribine (MZR) have potential application as antiherpes agents in combination with acyclovir (ACV). The effectivity of action of ACV on herpesvirus replication is improved after decreasing of the concentration of dGTP as a result of IMP dehydrogenase inhibition. The antiviral...

Herpes Simplex Virus (HSV) is the most common cause of non-epidemic, acute focal central nervous system infection. HSV type 1 (HSV-1 or Human Herpes Virus-1 [HHV-1]) is commonly associated with oropharyngeal infections, keratoconjunctivitis, and infections of the central nervous system, whereas HSV type 2 (HSV-2 or HHV-2) commonly produces genital infections. Severe disseminated HSV infection m...

Kaposi sarcoma is a tumour caused by human herpes virus 8, also known as Kaposi sarcoma-associated herpes virus. It usually affects the skin and oral mucosa; however, it can also sometimes affect the lungs, the liver, the stomach, the bowel, and lymph nodes. Several body sites may be affected simultaneously. The involvement of the tonsils is rare. We described an isolated localization of Kaposi...

Epigallocatechin gallate (EGCG) (Figure 1a) is the major catechin component of green tea (Camellia sinensis). It has been shown to have antiviral properties against DNA viruses such as herpes simplex virus (HSV; Herpesviridae) [1], adenovirus (Adenoviridae) [2], human papilloma virus (HPV; Papovaviridae) [3], and hepatitis B virus (HBV; Hepadnaviridae) [4], and RNA viruses such as influenza vir...