Although testosterone is associated with aggression in the popular imagination, previous research on the links between testosterone and human aggression has been inconsistent. This inconsistency might be because testosterone's effects on aggression depend on other moderators. In a large adolescent sample ( N = 984, of whom 460 provided hair samples), we examined associations between aggression ...

Adaptation to the space environment can sometimes pose physiological problems to International Space Station (ISS) astronauts after their return to earth. Therefore, it is important to develop healthcare technologies for astronauts. In this study, we examined the feasibility of using hair follicles, a readily obtained sample, to assess gene expression changes in response to spaceflight adaptati...

We propose a three-dimensional (3D) reconstruction method of human hair-shape from rotating head multiple video captured images and CT data. It is well known that no hair is present on the polygonal skin surface of the human head (3D-head) reconstructed from CT or MRI data. Our task is to reconstruct and add the hairshape on the 3D-head to create a realistic human head model for simulating post...

Hair follicle stem cells sustain growth and cycling of the hair follicle and are located in the permanent portion of the follicle known as the bulge. In this issue of the JCI, Ohyama et al. report the characterization of global gene expression patterns of human hair follicle stem cells after their isolation using sophisticated laser capture techniques to microdissect out bulge cells. They disco...

−Animals have typically been used in efficacy tests, but there are a number of dissimilarities between humans and animals. To overcome the problems associated with animal testing, a model which is reproduced in vitro with longterm culture with cell growth with in vivo activity must be developed. We made a gel-type dermal equivalent (DE) that contained dermal papilla cells (DPCs) or dermal sheat...

Dermal Papillae (DP) is a unique population of mesenchymal cells that was shown to regulate hair follicle formation and growth cycle. During development most DP cells are derived from mesoderm, however, functionally equivalent DP cells of cephalic hairs originate from Neural Crest (NC). Here we directed human embryonic stem cells (hESCs) to generate first NC cells and then hair-inducing DP-like...

In most of mammals, hair plays a very important role and protects them against physical forces, defends them against parasites and UV rays, provides heat conservation, and acts as a sensory organ. During the process of evolution, human hair lost these essential life-supporting functions. Human hair is now viewed as an object of aesthetic interest. However, androgenetic alopecia (male pattered h...

Human hair has played a significant role in forensic anthropology for decades. The morphological characteristics of human hair have long been utilized for personal identification in forensic investigations. With the development of better analytical techniques, hairs samples are also being used to understand and solve instances of poisoning, drug and substance abuse. This communication presents ...

We propose an efficient method for hair animation. The motion of hairs is modeled by a simplified physical simulation. Collision between hair and a human body or other objects is used to make a realistic hair animation. Fast collision detection is required because the number of hairs is very large. Therefore, a cylindrical representation of human body or other objects is created for efficient c...

The hair follicle undergoes lifelong cycling and growth. Previous studies have been focused on epithelial stem cells in the hair follicles. Neural crest stem cells (NCSCs) are pluripotent cells that can persist in adult tissues. We have previously demonstrated that human NCSCs can be isolated from hair follicles. Here, we present a protocol to isolate NCSCs from human hair follicles based on th...