Thromboxane and its receptor have emerged as key players in modulating vascular thrombotic events. Thus, a dysfunctional hTP genetic variant may protect against (hypoactivity) or promote (hyperactivity) vascular events, based upon its activity on platelets. After extensive in silico analysis, six hTP-α variants were selected (C(68)S, V(80)E, E(94)V, A(160)T, V(176)E, and V(217)I) for detailed b...

The effect of p-CPA and 5-HTP followed by p-CPA on sleep was studied in rats with olfactory bulb lesions (O.B. lesioned rats). In these rats, electrodes were chronically implanted to record the EEG (frontal cortex and dorsal hippocampus), the cervical electromyogram and eye movements. The REM sleep stage was selectively decreased from 24 to 32 hours after 200 mg/kg of p-CPA in the sham lesioned...

Abstract—Multiple channels present IEEE 802.11 MAC protocol designers with a number of options in their attempt to calm the effects of Hidden Terminal Problems (HTPs). The research on multi-channels shows that the effects of HTPs can be reduced and limited to Request To Send/Clear To Send (RTS/CTS) control packets. Unfortunately our analysis shows that data packets can be affected by HTPs. An e...

htp://iw c.oordjou oded from Article history: Available online 27 May 2011

Gene detection and structural annotations of plant model genomes is mainly done by bioinformatics groups running large sequences databases (essentially MIPS and TIGR). The raw material is the assembled genome sequences produced by standardized methods. Functional annotation is a more comple x process based on bioinformatic approaches, many heterogeneous data traditionally produced by biology la...

We use the presently observed number density of large X-ray clusters and linear mass power spectra to constrain the shape parameter (Γ), the spectral index (n), the amplitude of matter density perturbations on the scale of 8hMpc (σ8), and the redshift distortion parameter (β). The non-spherical-collapse model as an improvement to the Press-Schechter formula is used and yields significantly lowe...

BACKGROUND 5 Hydroxytryptophan (5-HTP) and tryptophan are so-called natural alternatives to traditional antidepressants, used to treat unipolar depression and dysthymia. OBJECTIVES To determine whether 5-HTP and tryptophan are more effective than placebo, and whether they are safe to use to treat depressive disorders in adults. SEARCH STRATEGY Trials were searched in computerized general (M...

We use the presently observed number density of large X-ray clusters and linear mass power spectra to constrain the shape parameter (Γ), the spectral index (n), the amplitude of matter density perturbations on the scale of 8h−1Mpc (σ8), and the redshift distortion parameter (β). The non-spherical-collapse model as an improvement to the Press-Schechter formula is used and yields significantly lo...

Common analytical challenges impact current work to estimate the cost of converting plant biomass to fermentable sugars. The most noteworthy are measuring cellulase and hemicellulase activities, cellulase and hemicellulase protein, biomass compositions (before and after pretreatment), and the products formed. The use of high-throughput (HTP) methods has shown considerable promise for improving ...