Investigation on natural sources from plants, animals, and microorganisms that produce gums mucilages goes increasing day by to check their pharmaceutical applications. Different have been studied for effects but the use of date palm (Phoenix dactylifera L.) mucilage as a excipient is still under cover. The aim this study was therefore evaluate compare flow property binding ability crude, purif...

Biopolymers reinforced with nanoparticle (NP) additives are widely used in tribological applications. In this study, the effect of NP additives on the tribological properties of a green lubricant hydroxypropyl methylcellulose (HPMC) composite was investigated. The IF-MoS₂ NPs were prepared using the newly developed gas phase sulfidation method to form a multilayered, polyhedral structure. The n...

   The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...

In this study, chocolate spreads were designed using oleogels with two oils (olive and sunflower), hydroxypropylmethylcellulose (HPMC) xanthan gum (XG), as structuring agents. Thus, the lipid profile of can be improved by totally or partially replacing coconut butter used in their preparation. Structural behaviour was analysed confocal laser scanning microscopy (CLSM), small amplitude oscillato...

We design and implement HPMC, a scalable hard particle Monte Carlo simulation toolkit, and release it open source as part of HOOMD-blue. HPMC runs in parallel on many CPUs and many GPUs using domain decomposition. We employ BVH trees instead of cell lists on the CPU for fast performance, especially with large particle size disparity, and optimize inner loops with SIMD vector intrinsics on the C...

Bioincompatibility of peritoneal dialysis fluids (PDF) has been linked to the presence of glucose degradation products (GDP). Previous experiments have shown that short-term exposure to several GDP at concentrations found in commercially available PDF had no significant effect on human peritoneal mesothelial cells (HPMC). During continuous ambulatory peritoneal dialysis, however, cells are cont...

PURPOSE To evaluate the ocular surface toxicity of two nitric oxide donors in ex vivo and in vivo animal models: S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylcysteine (SNAC) in a hydroxypropyl methylcellulose (HPMC) matrix at final concentrations 1.0 and 10.0 mM. METHODS Ex vivo GSNO and SNAC toxicities were clinically and histologically analyzed using freshly excised pig eyeballs. In vi...

Hypromellose, HPMC, is frequently used to control drug release from matrix tablet formulations. Drug is released by a combination of diffusion through and erosion of, the matrix and is usually measured invitro by separate dissolution and swelling/erosion studies. The present study was designed to measure matrix erosion, polymer dissolution and drug release kinetics and their inter-relationship ...

The ability of high viscosity hydroxypropylmethylcellulose (HPMC) to reduce postprandial glucose concentrations was assessed in patients with non-insulin-dependent diabetes (NIDDM) and healthy volunteers. The study design consisted of a two-way crossover, single-dose administration of 10 g prehydrated high viscosity HPMC, or placebo, with a standard carbohydrate-rich meal. In patients with NIDD...