The present study investigated the effects of valerian methanolic extract and valerenic acid on expression LL-37 gene protein in A549 MRC5 line cells. After preparing Valerian seeds, sowing them March 2020, harvesting rhizome October was prepared from by maceration method. content determined using high performance liquid chromatography (HPLC). Two cell lines (A549 MRC-5) were used to extract, M...

Reports on news of interest to MTTS Society members.

In this study, N-terminal site-specific mono-PEGylation of the recombinant lidamycin apoprotein (rLDP) of lidamycin (LDM) was prepared using a polyethyleneglycol (PEG) derivative (M w 20 kDa) through a reactive terminal aldehyde group under weak acidic conditions (pH 5.5). The biochemical properties of mPEG-rLDP-AE, an enediyne-integrated conjugate, were analyzed by SDS-PAGE, RP-HPLC, SEC-HPLC ...

The IEEE Microwave Theory and Technology Society (MTT-S) started as the “Professional Group on Techniques” (PG MTT) when founding committee received approval from then Institute of Radio Engineers (IRE) 7 March 1952. first meeting, held 1 May 1952, included Ben Warriner chair; Andre Clavier vice Bill Mumford secretary–treasurer; members Paul Coleman, Don King, Harry Marvin, Joe McCann, George R...

background and purpose: gastric cancer (gc) is one of the most common cancers worldwide and in iran. as conventional therapies such as surgery and chemotherapy are invasive with adverse effects, current studies are important as they are conducted to find natural compounds with few adverse effects. in this study, melittin with 26 amino acids was isolated and purified from bee venom and its effec...

THE TITLE COMPOUND (SYSTEMATIC NAME 12-{[2-(4-hydroxyphenyl)ethyl]aminomethyl}-4,8-dimethyl-3,14-dioxatricyclo[9.3.0.0(2,4)]tetradec-7-en-13-one monohydrate), C(23)H(31)NO(4)·H(2)O, was obtained by the reaction of tyramine with parthenolide. The configuration of the new chiral center in the title compound is R, establishing the stereospecificity of the amination reaction. The water molecule is ...

Multiple in vitro tests are widely applied to assess the anticancer activity of new compounds, including their combinations and interactions with other drugs. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay is one of the most commonly used assays to assess the efficacy and interactions of anticancer agents. However, it can be significantly influenced by compounds t...

Abstract Plectranthus barbatus Andrews (Lamiaceae) is widely distributed in the world and has a range of popular therapeutic indications. This work aimed to evaluate phytochemical characterization two leaf extracts P. barbatus, their antimicrobial, antineoplastic immunomodulatory potential. After collection, herborization obtainment aqueous extract (PBA) acetone:water 7:3 organic (PBO), was per...