background: allergens are mostly composed of glycoprotein structures. it is believed that glycan-specific antibodies may lead to false-positive reactions in immunoassays. in this study we investigated the glycosylation state of grape allergens as well as the presence of antibodies to cross-reactive carbohydrate determinants (anti-ccds) in sera from grape-sensitive individuals. methods: grape ex...

Despite the fact that lactate and pyruvate are potential substrates for energy production in vivo, our understanding of the control and regulation of carbohydrate metabolism is based principally on studies where glucose is the only available carbohydrate. Therefore, the purpose of this study was to determine the contributions of lactate, pyruvate, and glucose to energy production in the isolate...

The day to day variation in the energy and carbohydrate intake of 168 children with diabetes on Tyneside and Teesside was less than that of 405 non-diabetic children. It was, however, still considerable, the average range of carbohydrate intake over three days being 51 g. The variation in carbohydrate intake was not related to diabetic control nor to the families' knowledge of diabetes. Complia...

Trunk girdling can increase carbohydrate content above the girdling site and is an important strategy for inhibiting new shoot growth to promote flowering in cultivated litchi (Litchi chinensis Sonn.). However, girdling inhibits carbohydrate transport to the root in nearly all of the fruit development periods and consequently decreases root absorption. The mechanism through which carbohydrates ...

Ingestion of a drink containing sufficient carbohydrates can result in avoidance of exercise-induced hypoglycemia in type 1 diabetic individuals. In a previous study (1), we analyzed the effect of ingesting a drink with 6% carbohydrate (0.636 g/kg) on blood glucose concentration in type 1 diabetic adolescents during 60 min of moderate exercise and after 30 min of recovery. At the end of the tri...

The carbohydrate deficit induced by exercise is thought to play a key role in increased post-exercise insulin action. However, the effects of replacing carbohydrate utilized during exercise on postprandial glycaemia and insulin sensitivity are yet to be determined. This study therefore isolated the extent to which the insulin-sensitizing effects of exercise are dependent on the carbohydrate def...

It is well known that tumor cells express some aberrant glycans, termed tumor-associated carbohydrate antigens (TACAs). TACAs are good targets for the development of carbohydrate-based anticancer vaccines. However, one of the major problems is that carbohydrate antigens possess a weak immunogenicity. To tackle this problem, a number of unnatural N-modified S-linked STn analogues were designed a...

Aminoglycosides are a class of antibiotics that inhibit protein synthesis in bacteria by binding to the 30S ribosomal subunit. However, it has been reported that certain aminoglycosides have secondary effects on the cell’s overall carbohydrate concentration. Previous studies have also reported an increase in capsule size. This study attempted to investigate the effects of kanamycin and streptom...