Influenza A virus (IAV) lacks the enzyme for adding 5' caps to its RNAs and snatches the 5' ends of host capped RNAs to prime transcription. Neither the preference of the host RNA sequences snatched nor the effect of cap-snatching on host processes is completely defined. Previous studies of influenza cap-snatching used poly(A)-selected RNAs from infected cells or relied on annotated host genes ...

Perkinsus marinus is a protozoan parasite that causes high mortality in its commercially and ecologically important host, the Eastern oyster Crassostrea virginica. In order to understand the host-parasite relationship in lipid metabolism, the ability of P. marinus to synthesize phospholipids from polar headgroup precursors was investigated. Pulse/chase experiments were conducted using radiolabl...

Phenotypic variation is common among conspecifics from the same population, but its causes are not always clear. Parasites may often play a role, as their ability to induce phenotypic changes in their hosts is well established, though not widely acknowledged among marine ecologists. Here, we tested for a possible role of parasites as determinants of marked colour polymorphism, as well as variat...

Helicobacter pylori is an important human pathogen which causes both gastric and duodenal ulcers and is associated with gastric cancer and lymphoma. This microorganism synthesizes fucosylated oligosaccharides, predominantly the Galb-1,4GlcNAc (Type II) blood group antigens Lewis X and Y, whereas a small population also expresses the Galb-1,3GlcNAc (Type I) blood group antigens Lewis A and B. Th...

Most parasitoids of aphids are small wasps belonging to the families Braconidae or Aphelinidae. However, some dipteran parasitoids are also known to use aphids as hosts. We describe and give life-history information on a new species of aphid parasitoid, Endaphis fugitiva Gagné and Muratori, found to parasitize the banana aphid, Pentalonia nigronervosa Coquerel, the vector of banana bunchy top v...

A chimeric oxygenase, in which the P450cam domain was fused to the reductase host domains of a P450RhF from Rhodococcus sp. strain NCIMB 9784 was optimised to allow for a biotransformation at 30 mM substrate in 80% overall yield, with the linker region between P450 and FMN domain proving to be important for the effective biotransformation of (+)-camphor to 5-exo-hydroxycamphor.

This data article contains data related to the research article entitled "Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis" [1]. We report measurements on tenocyte viability, metabolic activity and proliferation on substrates with different topographies. We also report the effect of substrates with different topographies on host cells in a subcu...

Plasmodium falciparum has limited capacity for de novo amino acid synthesis and rely on degradation of host hemoglobin to maintain protein metabolism and synthesis of proteins. M1 alanine aminopeptidase enzyme of the parasite involved in the terminal degradation of host hemoglobin was subjected to in silico screening with low molecular weight protease inhibitors. The km (avg) of the enzyme M1 a...

Pin 1 is an enzyme that specifically catalyzes the cis-trans isomerization of phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif in its substrate proteins. Recent studies demonstrate that stability of several viral proteins is regulated by phosphorylation-dependent prolyl-isomerization by a host factor Pin1. Pin1 is now positioned as an important modulator of the molecular crosstalk b...

this guide to the identification of iranian freshwater snails has been prepared with aim of helping individuals involved in field work, but who have had no specialized training in taxonomy to differentiate snail specimens which they collect to certain groups by means of simple identification key. the guide pays special attention to the principal snail groups which transmit human schistosomiasis...