Plant diseases caused by pathogenic bacteria or fungi cause major economic damage every year and destroy crop yields that could feed millions of people. Only by a thorough understanding of the interaction between plants and phytopathogens can we hope to develop strategies to avoid or treat the outbreak of large-scale crop pests. Here, we studied the interaction of plant-pathogen pairs at the me...

the entomopathogenic-fungus-life cycle is associated with the synthesis and secretion of a number of toxic metabolites, including extracellular enzymes and the low-molecular weight compound (toxin). the potential for a successful pathogen relies on the ability to overcome the various host-defence systems. interaction between the fungus, tolypocla-dium (deuteromycetes), its secondary metabolite,...

Brucella is an intracellular bacterium that causes chronic brucellosis in humans and various mammals. The identification of host-Brucella interaction is crucial to understand host immunity against Brucella infection and Brucella pathogenesis against host immune responses. Most of the information about the inter-species interactions between host and Brucella genes is only available in the text o...

Protein-protein interactions (PPIs) play a vital role in initiating infection in a number of pathogens. Identifying which interactions allow a pathogen to infect its host can help us to understand methods of pathogenesis and provide potential targets for therapeutics. Public resources for studying host-pathogen systems, in particular PPIs, are scarce. To facilitate the study of host-pathogen PP...

Adherence molecules are key players in pathogen-host interactions. These are usually surface-exposed structures that facilitate adherence to host cells, or target host serum proteins of the extracellular matrix. Our knowledge of the function of pneumococcal cell-surface structures, and the basic mechanisms underlying their interaction with host receptor molecules has dramatically increased, thr...

ABDUL HANNAN BASIT, WAJID ARSHAD ABBASI, AMINA ASIF, AND FAYYAZ UL AMIR AFSAR MINHAS † Biomedical Informatics Research Laboratory, Department of Computer and Information Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan Department of Electrical Engineering, Pakistan Institute of Engineer-ing and Applied Sciences (PIEAS), Nilore, Islamabad, 440...

the observations that DCs are recruited to the lamina propria of the small intestine after bacterial infection, and the number of DCs recruited depends on the pathoMaria Rescigno1,3 and Persephone Borrow2,3 1 Department of Bioscience and Biotechnology U3 University of Milano-Bicocca genicity of the microorganisms encountered. In line with Piazza della Scienza, 2 this, it has been shown that bac...

HBV is a hepatotropic and non-cytopathic virus that causes more than one million deaths annually from liver cirrhosis and hepatocellular carcinoma. As the virus itself is non-cytopathic, it is widely accepted that both viral control and liver pathology are mediated by the host immune system. Until recently, the focus has been on the crucial role of adaptive immune responses in controlling HBV i...