Introduction: Secondary hyperparathyroidism due to vitamin D deficiency (VDD) is thought play a role in glucose homeostasis. The aim of this study was determine the association parathormone and with prediabetes its different cardiovascular risk factors. Methods: This crosssectional conducted among 117 adults newly detected prediabetes. Participants were recruited consecutively from Department E...

Abstract Objective: Homeostasis model assessment of insulin resistance (HOMA-IR) is a simple and practical method for estimation of insulin resistance (IR), but a reliable reference interval (RI) of HOMA-IR is needed to deduce the threshold level to define IR. This RI has been controversial in different populations and even more divergent when considering factors like age, gender and body mass...

combating desertification which is a serious threat for the environment and human welfare requires understanding complex issues of this phenomenon using evaluation, awareness of severity of it's processes and determination of it's factors. so here, after recognizing the characteristics of the region showing existence desertification, we assess its current status with emphasis on clima...

background: leptin is an adipokine that circulates in a free form and bound to a soluble leptin receptor. patients with polycystic ovary syndrome have increased insulin resistance and high incidence of obesity. objective: this study was carried out to evaluate levels of leptin and free leptin in women with polycystic ovarian syndrome (pcos) and note any relationships with insulin resistance and...

background: polycystic ovary syndrome (pcos) is the most common endocrine disorder in females of reproductive age. insulin resistance is a frequent metabolic disturbance in pcos. vitamin d deficiency is a common problem. accumulating evidence suggests that vitamin d has a role on insulin sensitivity so may contribute to reduction of hyperandrogenemia. objective: the aim was to determine the eff...

Background and aims The lower 25-Hydroxyvitamin D(25(OH)D) is being suggested as a risk factor for Type 2 diabetes, but there is not well construed for its relationship. Therefore, we aimed to assess the association among 25(OH)D level, metabolic syndrome components [Waist circumference (WC), Blood pressure, Triglycerides, Glucose, HighDensity lipoprotein Cholesterol], and insulin resistance in...

OBJECTIVE To determine the association of insulin sensitivity and pancreatic beta-cell function parameters assessed by the homeostasis model assessment (HOMA) and glycemic control, and their potential utilization in the clinical care of patients with type 2 diabetes mellitus. MATERIAL AND METHOD The HOMA indices were assessed in 204 (62 males, 142 females) type 2 diabetic outpatients aged 60....

Premature pubarche can be benign, or it can be an early marker of insulin resistance in some girls. The aim of this study was to evaluate insulin resistance in prepubertal girls presenting with premature pubarche (n = 19; mean age = 6.93 +/- 1.78) as compared to age- and Tanner stage-matched controls (n = 10; mean age = 7.55 +/- 1.32) using indirect insulin resistance parameters. Two groups wer...

RESEARCHDESIGNANDMETHODSdOne-hundred three participants were randomized to receive either PRT or sham exercise 3 days per week for 12months. Homeostatic model of assessment 2 (HOMA2-IR) and glycosylated hemoglobin (HbA1c) were used as indices of IR and glucose homeostasis. Skeletal muscle mass (SkMM) and total fat mass were assessed using bioelectrical impedance. Visceral adipose tissue, mid-th...