We compared the electrophysiological responses to serotonin (5-HT) of neonatal and juvenile rat hypoglossal motoneurons (HMs) by using intracellular recording techniques in a brainstem slice preparation. In neonatal HMs (</=P8), 5-HT caused a substantial decrease in the amplitude of spike afterhyperpolarization (AHP) that was associated with an increase in the minimal repetitive firing frequenc...

In clinical diagnostics, single nucleotide polymorphism (SNP)-based microarray analysis enables the detection of copy number variations (CNVs), as well as copy number neutral regions, that are absent of heterozygosity throughout the genome. The aim of the present study was to evaluate the effectiveness and sensitivity of SNP‑based microarray analysis in the diagnosis of hydatidiform mole (HM). ...

Sustained activity of mammalian methionine synthase (MS) requires MS reductase (MSR), but there have been few studies of the interactions between these two proteins. In this study, recombinant human MS (hMS) and MSR (hMSR) were expressed in baculovirus-infected insect cells and purified to homogeneity. hMSR maintained hMS activity at a 1:1 stoichiometric ratio with a K(act) value of 71 nM. Esch...

The co-condensation of a tetraethoxysilane molecule on a neutral n-octylamine surfactant template is a convenient synthetic methodology for mesostructured material preparations. Distinct routes of template removal were investigated. The neutral surfactant was removed by calcination, hot solvent extraction, heating at 150 uC, in vacuo at room temperature and at 100 uC, and air drying, with the p...

The aim of the Health and Memory Study (HMS) of Nord-Trøndelag, Norway, was primarily to establish a database suitable as basis for a large number of studies on dementia. Data from the HMS study were collected via questionnaires and examinations during the period from 1995 to 2011. The dementia panel consists of 620 participants residing in nursing homes and 920 participants referred to memory ...

Heat-killed Pseudomonas aeruginosa are phagocytized much more slowly by human polymorphonuclear leukocytes than are the live organisms. The post-phagocytic increase in hexose monophosphate shunt activity (HMS) parallels the ingestion of the bacteria. The addition of serum to the live organisms causes a marked increase in both ingestion and cellular HMS activity; serum actually causes an inhibit...

−Three kinds of biochars (called poplar branch biochar (PBC), water hyacinth biochar (WHC), and corn straw biochar (CSC)) were prepared in a fixed-bed pyrolyzer at different pyrolysis temperature of 300-700 C. The effects of biochar species, pyrolysis temperature and biochar addition on adsorption characteristics of typical heavy metals (HMs) of Pb and Zn in vegetable soil (collected from lead-...

This paper deals with a real-time scheduling system of holonic manufacturing systems (HMSs), which were proposed by an international cooperative research consortium called The HMS Consortium for Autonomous Distributed Management and Control of the Manufacturing Systems. The scheduling system generates real-time suitable production schedules, based on decision making by individual constituents n...