Background HMF oxidase (HMFO) from Methylovorus sp. is a recently characterized flavoprotein oxidase. HMFO is a remarkable enzyme as it is able to oxidize 5-hydroxymethylfurfural (HMF) into 2,5-furandicarboxylic acid (FDCA): a catalytic cascade of three oxidation steps. Because HMF can be formed from fructose or other sugars and FDCA is a polymer building block, this enzyme has gained interest ...

The food processing contaminants 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), 5-hydroxymethylfurfural (HMF) and 2,5 dimethylfuran (DMF) are potentially both mutagenic and carcinogenic in vitro and/or in vivo, although data on DMF is lacking. The PHIP metabolite N-hydroxy-PhIP and HMF are bioactivated by sulfotransferases (SULTs). The substrate specificity and tissue distribution of S...

OBJECTIVES To examine changes in cerebrovascular pressure transmission derived from arterial blood pressure (ABP) and intracranial pressure (ICP) recordings by autoregressive moving average modeling technique. METHODS Digitized ICP and ABP recordings were obtained from patients with brain injury. Two groups were defined: Group A with 4 patients who demonstrated plateau waves, and Group B with...

Background: Honey is a natural product, but it can be adulterated or heat-treated, both of which damage the properties of the original product. This research was focused on the evaluation of quality parameters of some commercial honeys produced in México.  Methods: Fifteen samples of commercial honeys available in Mexican market were collected. Some physicochemical parameters were determined, ...

Background: Pekmez is an important fruit-based food of Turkish culinary culture. The aim of this study is to determine the levels of acrylamide (AA), 5-hydroxymethyl-2-furfural (HMF) and other selected parameters in grape, mulberry and carob Pekmez. Methods: AA and HMF were analyzed by Liquid Chromatography and High Performance Liquid Chromatography, respectively. Also, glucose, fructose, pH, ...

Oxidative conversion of 5-hydroxymethylfurfural (HMF) is of biotechnological interest for the production of renewable (lignocellulose-based) platform chemicals, such as 2,5-furandicarboxylic acid (FDCA). To the best of our knowledge, the ability of fungal aryl-alcohol oxidase (AAO) to oxidize HMF is reported here for the first time, resulting in almost complete conversion into 2,5-formylfuranca...

the purpose of this study was to develop a sensitive and fast microdialysis coupled with high-performance liquid chromatographic (hplc) method for determination of 5-hydroxymethyl-2-furaldehyde (5-hmf) in free-moving rats after i.g. administration of the aqueous extract of crud fructus corni and its processed products of jiuzheng pin (jzp). the concentration of 5-hmf in free-moving rats after i...

The use of biomass-derived compounds as substitutes of pet roleum has received much a t tent ion1)~4). Because of the complex nature of biomass, the conversions of biomass to chemicals usually start with the production of small molecules called platform chemicals by thermal, chemical or biological processing5). Among these platform chemicals, furfural6) and 5hydroxymethylfurfural (HMF)7) are es...

We study chaos in the Hamiltonian Mean Field model (HMF), a system with many degrees of freedom in which N classical rotators are fully coupled. We review the most important results on the dynamics and the thermodynamics of the HMF, and in particular we focus on the chaotic properties. We study the Lyapunov exponents and the Kolmogorov– Sinai entropy, namely their dependence on the number of de...