proceedings elucidate a central historic paradox articulated by the keynote speaker. Wilbur Cohen was former HEW administrator and Secretary under Presidents Kennedy and Johnson. He directed passage of the Medicare law, then saw it implemented. Cohen theorized in his keynote address that Medicare "was born more of social conviction than of research findings". Ironically this publication, which ...

This research extends existing heuristic inspection with criteria grids to include emotional and persuasiveness factors. We first review the existing criteria and categorize them into four major groups, aligned along a historic perspective of HCI. Hence, we find criteria that fall into (a) accessibility, (b) usability, then (c) affective, and finally (d) persuasive categories. In the second par...

Stirrup and Underwood make their argument for SPECT imaging from the perspective of ‘‘If it ain’t broke, don’t fix it.’’ They acknowledge the historic value of myocardial perfusion SPECT, as well as the limitations of SPECT technology. Their comments only partially reflect the societal yearning for more precise answers about the presence, extent, and prognosis of patients with coronary artery d...

Sequencing of RNA (RNA-Seq) was invented approximately 1 decade ago and has since revolutionized biological research. This update provides a brief historic perspective on the development of RNA-Seq and then focuses on the application of RNA-Seq in qualitative and quantitative analyses of transcriptomes. Particular emphasis is given to aspects of data analysis. Since the wet-lab and data analysi...

By the end of last month, the successful era of President Willem Duisenberg at the helm of the European Central Bank came to an end. At the beginning of this month, Mr. Jean-Claude Trichet became second President of the European Central Bank. Certainly, already this change at the top of the ECB provides a good opportunity for both looking back and looking into the future. Moreover, from a broad...

The rapid development of climate policies and the need to understand the dynamics of climate change have highlighted and shaped the role of land use, land-use change and forestry dynamics (LULUCF), making it an issue of global importance. As a consequence, LULUCF has become a central topic in economic theory and in environmental sciences. The attention is focused on creating and expanding compr...

This paper explores how the dynamics of complex biological processes can be modeled as an organisation of multiple agents. This modelling perspective identifies organisational structure occurring in complex decentralised processes and handles complexity of the analysis of the dynamics by structuring these dynamics according to an organisational structure. More specifically, dynamic properties a...