Non-steroidal anti-inflammatory drugs (NSAIDs) are known to cause gastrointestinal damage. New anti-inflammatory drugs have been developed in an attempt to improve their gastrointestinal side effect profile which however failed to do so. Therefore, the objective of the present study was to compare the effect of three different NSAIDs, aspirin, nimesulide and celecoxib on the intestinal brush bo...

The present study was designed to evaluate the cardioprotective effects of Lagenaria siceraria fruit juice in isoproterenol-induced myocardial infarction. Rats injected with isoproterenol (200 mg/kg, s.c.) showed a significant increase in the levels of serum uric acid, tissue Na(++) and Ca(++) ions and membrane-bound Ca(+2)-ATPase activity. A significant decrease in the levels of serum protein,...

This study investigated whether the coadministration of vitamin E (VitE) diminishes harmful effects provoked by plasticizer bisphenol S (BPS) in serum metabolites related to hepatic and renal metabolism, as well endocrine pancreatic function diabetic male Wistar rats. Rats were divided into five groups (n = 5–6); first group was healthy rats (Ctrl group). The other four induced with 45 mg/kg bw...


 Aim: The present study was carried out to determine the protective potential of Lycopene enriched tomato extract (LycT) against hepatic and renal damage caused in mice by dexamethasone administration.
 Study Design: Male LACA were randomly divided into four treatment groups (n=6-7 animals per group) depending upon they received. Group I (control) served as control orally administere...

Aim To investigate the vascularization capacity of a decellularized dental pulp matrix (DDP) bovine origin seeded with human stem cells (hDPSCs) in vitro and to present preliminary vivo findings. Methodology Bovine pulps were then analysed using histological staining DNA quantification. The resultant DDPs characterized immunohistochemical for retention vascular endothelial growth factor A (VEGF...

Quinalphos (QP) is commonly used for pest control in the agricultural fields surrounding freshwater reservoirs. This study was conducted to evaluate the chronic toxicity of this pesticide on blood parameters and some organs of silver barb, Barbonymus gonionotus. Fish were exposed to two sublethal concentrations, 0.47 ppm and 0.94 ppm, of QP for a period of 28 days. All the blood parameters (red...

Different herbal Plants are used globally for safe and natural source of medicine from ancient ages. Jussiaea repens L, is a medicinal herb that has been reported to have non toxic antigonadal activity, which reduced the sperm count, motility, viability and morphological alteration of spermatozoa in rats. It also alters histoarchitechture visà-vis functions of testicular tissues by altering the...

Background: Methotrexate (MTX) is used as an antineoplastic drug in the treatment of various cancers and non-cancerous diseases. Ovarian ablation is considered to be effective in delaying recurrence of cancer and increasing survival in young women. When added to chemotherapy, it is less clear that this technique is effective. Uniqueness of the present study is that we used ovariectomized (OVX) ...

This study was done to evaluate the effects of lead nitrate and mercury chloride in testis tissues of Wistar rats. Lead nitrate and mercury chloride are widely used heavy metals in industry. Oral lead and mercury administrations to adult male rats at doses 45 mg/kg bw and 0.02 mg/kg bw, respectively for 4 weeks caused a significant increasing in MDA levels and antioxidant enzyme activities (SOD...