We have studied subunit-subunit interactions in bovine lutropin (bLH) through characterization of carbodiimide-cross-linked derivatives (EDCbLH). Spectrophotometric titrations indicated that an additional tyrosine residue ionizes abnormally in EDCbLH compared to native bLH. Furthermore, only five out of seven tyrosines in the cross-linked derivative were ionized at pH 13. Treatment with tetrani...

BACKGROUND In women with chronic anovulation, the choice of the FSH starting dose and the modality of subsequent dose adjustments are critical in controlling the risk of overstimulation. The aim of this prospective randomized study was to assess the efficacy and safety of a decremental FSH dose regimen applied once the leading follicle was 10-13 mm in diameter in women treated for WHO Group II ...

BACKGROUND/AIM Nipple discharge syndrome is a clinical entity capable of presenting various disorders such is mammary infection (nonpuerperal and puerperal mastitis), intraductal papillomas, fibrodenoma, breast cancer and hyperprolactinemia syndrome. The aim of the study was to determine differences in cytological features of mammary secretion in patients with hyperprolactinemia and those with ...

Antiinflammatory mechanisms are important in ovulation and may be regulated by cortisol (F). We previously showed that after administration of human (h)CG for ovulation induction, luteinized granulosa cells (LGC) abundantly express 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) messenger RNA but not 11betaHSD type 2 (11betaHSD2) messenger RNA. 11ssHSD1 is responsible for the reversible...

Gynec. Invest. 1974;5:7-64 Scientific Abstracts 1 Systemic and Pulmonary Hemodynamic Resposes to Neurotransmitters during Fetal Development B. Nuwayhid, C. Brinkman, III, J. Bevan, C. Su and N.S. Assali Department of Obstetrics-Gynecology and Pharmacology, University of California, Los Angeles, Calif., USA Development of vascular receptors in pulmonary and systemic circulations and their reacti...

Gynec. Invest. 1974;5:7-64 Scientific Abstracts 1 Systemic and Pulmonary Hemodynamic Resposes to Neurotransmitters during Fetal Development B. Nuwayhid, C. Brinkman, III, J. Bevan, C. Su and N.S. Assali Department of Obstetrics-Gynecology and Pharmacology, University of California, Los Angeles, Calif., USA Development of vascular receptors in pulmonary and systemic circulations and their reacti...