نتایج جستجو برای: hexosaminidase activity

تعداد نتایج: 1134871  

Journal: :Acta Biochimica Polonica 1999

Journal: :Annals of Indian Academy of Neurology 2006

2017
Li-Li Hong Hao-Bing Yu Jie Wang Wei-Hua Jiao Bao-Hui Cheng Fan Yang Yong-Jun Zhou Bin-Bin Gu Shao-Jiang Song Hou-Wen Lin

Hipposponlachnins A (1) and B (2), possessing an unprecedented tetracyclo [9.3.0.02,8.03,7] tetradecane ring system, and the probable biogenetic precursor [3, (1R*,2E,4R*,7E,10S*,11S*,12R*)-10, 18-diacetoxydolabella-2,7-dien-6-one] of 1‒2 were isolated from the South China Sea marine sponge Hippospongia lachne. The structures of the novel compounds were determined using integrated spectroscopic...

Journal: :Clinical chemistry 1973
J A Lowden M A Skomorowski F Henderson M Kaback

In serum there are two classes of hexosaminidase. One of these is heat-labile and is inactive in children with Tay-Sachs disease. Serum from heterozygotes for Tay-Sachs disease has half the normal activity of the heat-labile enzyme. The heat-labile enzyme can be inactivated by heating serum diluted in buffer for 5 mm at 60 #{176}C. We have used this property to develop a reliable, fully automat...

Journal: :The Biochemical journal 2011
Tian Liu Haitao Zhang Fengyi Liu Lei Chen Xu Shen Qing Yang

Chitinolytic β-N-acetyl-D-hexosaminidase is a branch of the GH20 (glycoside hydrolase family 20) β-N-acetyl-D-hexosaminidases that is only distributed in insects and micro-organisms, and is therefore a potential target for the action of insecticides. PUGNAc [O-(2-acetamido-2-deoxy-D-glucopyransylidene)-amino-N-phenylcarbamate] was initially identified as an inhibitor against GH20 β-N-acetyl-D-h...

Journal: :Investigative ophthalmology & visual science 2009
Michelle L McDonald Yanru Wang Shivaram Selvam Tamako Nakamura Robert H Chow Joel E Schechter Samuel C Yiu Austin K Mircheff

PURPOSE Lacrimal immunohistopathology has diverse clinical presentations, suggesting that inflammatory mediators exert diverse influences. Chronic exposure to agonistic acetylcholine receptor autoantibodies has been studied previously; the present work addressed mediators that signal through other G protein-coupled receptors. METHODS Acinus-like structures and reconstituted acinar epithelial ...

Journal: :Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2004
Yukio Tanaka Shuzo Taguchi Seisaku Yoshida Shinjiro Hori

The effects of foods and chemicals related to food hygiene on degranulation were evaluated using a method for assaying the enzyme activity of beta-hexosaminidase as an index of chemical mediator release from RBL-2H3 cells in vitro. Using a previously developed assay system, we had found a large number of inhibitors and promoters of degranulation of RBL-2H3 cells. In the present study, we examin...

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