Two platelet-activating factor (PAF) analogs containing a methyl group at C2 of the glycerol moiety were synthesized, and some of their biochemical properties were investigated. 1-O-Hexadecyl-2-C,O-dimethyl-rac-glycero-3-phosphocholine (2-methyl-2-methoxy PAF) was prepared in a synthetic scheme beginning with the etherification of 2-methylpropen-1-ol. A reaction sequence involving hydroxylation...

We demonstrate the efficient incorporation of PS-tethered cadmium sulfide nanorods (PS-CdS NRs) into polystyrene-block-poly(ethylene oxide) (PS-b-PEO) ultralong cylindrical micelles by solvent evaporation-driven self-assembly. The hexadecyl trimethyl ammonium bromide (CTAB) was used as the surfactant in chloroform-in-water emulsions. It is a prerequisite to improve the enthalpic compatibility b...

Furan-2,5-diylbis(phenylmethanol) is a key intermediate to access sub(oxa)porphyrins. Previously, this was accessible from fossil-derived furan using highly dangerous lithium reagents. Presently, we have produced cashew apple bagasse (CAB), via the formation of 5-hydroxymethylfurfural (HMF). CAB non-food biomass containing cellulose and hemicellulose. From CAB, obtained HMF in yield 310 mg/g CA...

2,4-Dichloro-, 4,6-dichloro-, 2,4,6-trichloroand tetrachloropyrimidine undergo nucleophilic displacements by 4-(dimethylamino)pyridine to give (pyrimidine-2,4-diyl)-1,1’-bis[4-(dimethylamino)pyridinium] dichloride, (pyrimidine-4,6-diyl)-1,1’-bis[4-(dimethylamino)-pyridinium] dichloride, (pyrimidine-2,4,6-triyl)-1,1’,1”-tris[4-(dimethylamino)pyridinium] trichloride, and (5chloropyrimidine-2,4,6-...

Simultaneous spectrophotometric determination of Mn, Zn and Co was studied by two methods, classical partial least-squares (PLS) and kernel partial least-squares (KPLS), with 2-(5-bromo-2- pyridylazo)-5-diethylaminephenol (5-Br-PADAP) and cetyl pyridinium bromide (CPB). Two programs, SPGRPLS and SPGRKPLS, were designed to perform the calculations. Eight error functions were calculated for deduc...

The reaction of a cobalt(II) salt with 4-(dimethyl-amino)pyridinium hydro-bromide perbromide yielded the title compound, (C(7)H(11)N(2))[CoBr(3)(C(7)H(9.1)Br(0.9)N(2))]. In the anion, the Co(II) atom is coordinated in a distorted tetra-hedral geometry by three Br atoms and the pyridine N atom of a bromine-substituted 4-(dimethyl-amino)pyridine mol-ecule, whose formation probably results from an...

In the title salt, C37H51N2O10(+)·Br(-), the 1,4-dihydro-pyridine (1,4-DHP) ring adopts a slighly puckered boat conformation. The N and opposite C atoms deviate from the least-squares plane calculated through the four other ring atoms by 0.068 (5) and 0.224 (5) Å, respectively. The orientation of both C=O groups is similar (cis with respect to the double bonds of 1,4-DHP. The pyridinium ring ha...

Detergent-based mixtures and pure surfactants used as decontaminants in mass casualty scenarios were investigated for their acute 24 h toxicity. Commercial detergents Neodekont, Argos, Dermogel, and FloraFree were tested in male Wistar rats after percutaneous, peroral and intramuscular administration. Pure surfactants althosan MB, sodium alkylbenzene sulphonate, triton X, benzyl dimethyl dodecy...

Thiols have been of enduring interest for many years because of their role in biological and pharmacological processes. Monitoring of total thiols content is very important in order to understand their function in living organisms. This paper describes the spectrophotometric method for the determination of total thiols concentration in urine. The method is based on derivatization with 1-benzyl-...