Polyadenylate sequences have been found covalently linked in heterogeneous DNA-like nuclear RNA of HeLa cells. This poly(A) material seems homogeneous in size and accounts for about 0.5% of such RNA. Similar poly(A) sequences were found in rapidly-labeled polyribosomal RNA, thought to be messenger RNA. A possible model for mRNA synthesis from large heterogeneous nuclear RNA precursor molecules ...

Two recent advances—the use of functionally gradient materials in parts and layered manufacturing technology— have brought to the forefront the need for design and fabrication methodologies for heterogeneous objects. However, current solid modeling systems, a core component of computer-aided design and fabrication tools, are typically purely geometry based, and only after the modeling of produc...

Poly (vinylpyrrolidone)-grafted silica as an organic-inorganic hybrid material was used as an effective heterogeneous polymeric cosolvent catalyst in organic reactions. This modified silica catalyzed nucleophilic displacement of alkyl halides for easy preparation of alkyl thiocyanates, alkyl cyanides, alkyl azides and alkyl aryl ethers. Furthermore, the catalyst was applied for the conversion o...

Solid modeling of objects forms an important task in design and manufacturing. Recent developments in the field of layered manufacturing have shown potential for the physical realization of heterogeneous (multi-material) objects. Thus, there is a need to represent material information as an integral part of the CAD model data. Information models for the representation of product data are being ...

The development of biomedical scaffolds mimicking a heterogeneous cellular microenvironment for a specified regulation of cell-fates is very promising for tissue engineering. In this study, three-dimensional scaffolds with heterogeneous microstructure were developed using a DMD-PP apparatus. During the fabrication process, this apparatus can efficiently switch monomers to form microstructures w...

An extension of the generalized finite element method to the class of mixed finite element methods is presented to tackle heterogeneous systems with nearly incompressible non-linear hyperelastic material behavior. In particular, heterogeneous systems with large modulus mismatch across the material interface undergoing large strains are investigated using two formulations, one based on a continu...

poly (vinylpyrrolidone)-grafted silica as an organic-inorganic hybrid material was used as an effective heterogeneous polymeric cosolvent catalyst in organic reactions. this modified silica catalyzed nucleophilic displacement of alkyl halides for easy preparation of alkyl thiocyanates, alkyl cyanides, alkyl azides and alkyl aryl ethers. furthermore, the catalyst was applied for the conversion o...

Structural hierarchy and material organization in design are traditionally achieved by combining discrete homogeneous parts into functional assemblies where the shape or surface is the determining factor in achieving function. In contrast, biological structures express higher levels of functionality on a finer scale through volumetric cellular constructs that are heterogeneous and complex. Desp...