This is a case report describing two cases of disciform corneal edema following uncomplicated selective laser trabeculoplasty (SLT) thought to be secondary to herpes simplex virus (HSV) given the presence of a dendrite, decreased corneal sensation, corneal thinning, and response to therapy with oral and topical antivirals. Corneal edema after SLT treatment has been reported before, but the etio...

The inflammatory response to herpes simplex virus infection of the cornea was studied in athymic nude (nu/nu) and heterozygote (nu/+) BALB/c mice. Although athymic mice were highly susceptible to HSV infection and died 13 to 17 days after corneal inoculation, they failed to develop necrotizing keratitis of the cornea. Heterozygote mice survived the initial virual infection, but many of these mi...

Kirwan, E. O'G.-" Epidemic Superficial Punctate Keratitis in Bengal." Prcc. All-India Obhthal. Soc., Vol. III, p. 1, 1933. Kuchner, K.-" Inoculations with Herpes Virus." Klin. Monatsbl. f. A tgenheilk., Vol. XCI, p. 485, 1933. Lloyd, R. I.-" Herpes and Allied Conditions." Amer. Ji. of Ophthal., Vol. XIV, p. 601, 1931. Moore, R. F -" Ocular Manifestations of Lesions of the Fifth Nerve." British ...

The authors have investigated the course of herpes simplex type 1 (HSV) keratitis in three different inbred strains of mice infected with four different HSV isolates. Severity of ocular disease and mortality is dependent upon both the virus isolate and the host strain. In particular, the likelihood of progression from self-limited dendritic keratitis to severe necrotizing stromal keratitis vari...

Herpes simplex virus type I (KOS) was instilled onto the eyes of rabbits with experimentally induced xerophthalmia (vitamin A deficient) and control animals fed a vitamin A supplemented diet. The severity of the herpes virus-induced corneal disease, assessed by biomicroscopic examination and by counting the number of corneal lesions as well as by determining the virus titers, was significantly ...

Abstract Background and Aims: Herpes simplex virus (HSV) is a common cause of corneal disease and is the leading infectious cause of corneal blindness among developed nations. This study is aimed to provide an estimation of the incidence of Herpes Simplex Virustype-1, 2(HSV1, 2) and Varicella Zoster Virus (VZV) in tears and swab from eye infection by polymerase chain reaction (PCR) in eye ...

Keratomycosis is a major cause ofvisual disability in developing countries(1). It is common in our country because of the tropical climate and a large agrarian population at risk. Since the first report ofkeratomycosis. by Professor Theodor Leber, fungi have been increasingly implicated in the cause ofcorneal ulcer (2,3), there has been a dramatic rise in frequency of these infections in the la...

PURPOSE To investigate the effect of Fas and Fas ligand (FasL) deficiency on the development of herpes stromal keratitis and on the von Szily model of herpes retinitis in C57BL/6 mice, which are ordinarily resistant to development of both of these herpetic diseases. METHODS Anterior chamber inoculation of the right eye of each mouse with various titers of HSV-1 (KOS strain) was performed. Bot...

Five out of 430 patients (1.16%) undergoing kidney transplantation developed an atypical clinical picture of herpetic dendritic keratitis within four weeks after surgery. It was manifested by multiple dendrites, located mainly in the corneal periphery or the limbus, developing in relatively uninflamed eyes. The response to acyclovir therapy was prolonged and took at least three weeks. Additiona...