We develop a system of equations to analyse the existence of genetic polymorphisms under disruptive selection in heterogeneous environments. These equations have both a genetic and a population density regulation component. In the absence of the genetic component, the equations reduce to a discrete time description of competition between interacting clonal lines or species. We use these equatio...

In this paper, a new approach to stability for fractional order control system is proposed. Here a dynamic system whose behavior can be modeled by means of differential equations involving fractional derivatives. Applying Laplace transforms to such equations, and assuming zero initial conditions, causes transfer functions with no integer powers of the Laplace transform variable s to appear. In ...

Hereditary transmission of bodily (physical) and behavioral (moral) features from parents to offspring became an independent subject of scientific theorizing only in the mid-decades of the nineteenth century. Only then did it become clear that the questions around the stability of species and the question about the contingent similarities responsible for family resemblance were tightly intermin...

Background & Aims: Nearly 30 hereditary disorders in humans result from an increase in the number of copies of simple repeats in genomic DNA, including fragile X syndrome, myotonic dystrophy, Huntington’s disease, and Friedreich’s ataxia. One the most frequently occurring types of mutation is trinucleotide repeat expansion. The present study was conducted with the aim of investigating the cause...

β/γ-Crystallins, the major structural proteins in human lens, are highly conserved in their tertiary structures but distinct in the quaternary structures. The N- and C-terminal extensions have been proposed to play a crucial role in mediating the size of β-crystallin assembly. In this research, we investigated the molecular mechanism underlying the congenital hereditary cataract caused by the r...

γD-crystallin is one of the major structural proteins in human eye lens. The solubility and stability of γD-crystallin play a crucial role in maintaining the optical properties of the lens during the life span of an individual. Previous study has shown that the inherited mutation G61C results in autosomal dominant congenital cataract. In this research, we studied the effects of the G61C mutatio...

A population-based, cross-sectional study was performed in southeast Norway, between January 2002 and February 2008, to identify subjects with hereditary ataxia and hereditary spastic paraplegia, and to estimate the prevalence of these disorders. Patients were recruited through colleagues, families, searches in computerized hospital archives and the National Patients' Association for Hereditary...

Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patien...

The panel covers genes associated with hereditary colorectal cancer syndromes, familial pancreatic cancer, hereditary diffuse gastric cancer and gastrointestinal stromal tumors. Also other syndromes associated with increased risk of gastrointestinal cancer are covered. The Hereditary Gastrointestinal Cancer Panel is suited for detecting heritable germline mutations and may not be used for the d...

We introduce the notions of τ -exceptional and signed sequences for any finite dimensional algebra. prove that a fixed algebra rank n , positive integer t ≤ there is bijection between set length (basic) ordered support -rigid objects with indecomposable direct summands. If hereditary, our coincide exceptional sequences. The latter were recently introduced by Igusa Todorov, who constructed simil...