The woodchuck hepatitis virus is a naturally occurring hepatitis B-like virus that infects the eastern woodchuck. Direct immunofluorescence staining for woodchuck hepatitis virus core antigen in liver biopsies demonstrated the presence of this antigen in 14 of 17 chronically infected woodchucks, and in 8 of 10 woodchucks undergoing acute infections. Fluorescent localization of woodchuck hepatit...

viral hepatitis is one of five infectional factors cause early death in all over the world. every day at least one million people die because of viral hepatitis. six hepatitis viruses have been known until now. they are a, b, c, d, e, g, and it is probable that at least two other kinds i.e. f, and h, will be known soon. only hepatitis b is a dna virus, and the others are rna viruses. all viruse...

conclusions fulminant hepatitis b is associated with distinct mutational patterns of hbv, underlining that genomic diversity of the virus is an important factor determining its pathogenicity. results the most commonly detected diversities affect regulatory motifs of hbv in the core and s region, indicating that these alterations may convert the virus to an aggressive strain. moreover, mutations...