Hepatic cancer or liver cancer is a cancer that begins in the cells of the liver. Liver cancer consists of malignant hepatic tumors in or on the liver. Hepatocellular carcinoma (HCC) is the most common form of liver cancer, which begins in the main type of liver cell (hepatocyte). HCC classified as the fourth most common cancer in the world and is responsible for about a quarter of a million de...

Biodegradable polymer nanoparticle drug delivery systems provide targeted drug delivery, improved pharmacokinetic and biodistribution, enhanced drug stability and fewer side effects. These drug delivery systems are widely used for delivering cytotoxic agents. In the present study, we synthesized GC/5-FU nanoparticles by combining galactosylated chitosan (GC) material with 5-FU, and tested its e...

CONTEXT A case of autoimmune pancreatitis develops a hepatic metastasis of bladder cancer resected over 5 years before, mimicking a pseudotumor of the liver. CASE REPORT A 71-year-old man with a surgical history of bladder cancer (pT4, G2>3, N (+)) later developed autoimmune pancreatitis. Diagnosis of autoimmune pancreatitis was not problematic; however, a variety of systemic disorders app...

OBJECTIVE The aim of this study was to evaluate the safety and efficacy of ultrasound-guided high-intensity focused ultrasound therapeutic ablation of solid tumors in difficult locations. SUBJECTS AND METHODS A procedure was performed with a focused ultrasound tumor therapeutic system which provides real-time ultrasound guidance. All patients underwent MDCT or MRI, and some patients underwent...

Because liver involvement in patients with metastatic cancer has limited options and poor outcomes, we conducted a phase I study to determine the safety, activity, and pharmacokinetic characteristics of hepatic arterial infusion of nanoparticle albumin–bound paclitaxel (HAI nab-paclitaxel). Cohorts of three patients having predominant hepatic metastases received HAI nab-paclitaxel at three dose...

arsenic exposure mainly through food and water has been shown to be associated with increased incidence of numerous cancers and non-cancer harmful health. it is also used in cancer chemotherapy and treatment of several cancer types due to its apoptogenic effects in the various cancer and normal cell lines. we have already reported that liver is the storage site and important target organ in as ...

Kaposi sarcoma (KS) is an aggressive cancer caused by human herpesvirus-8, primarily seen in immunocompromised patients. As opposed to the well-described cutaneous manifestations and pulmonary complications of KS, hepatic KS is rarely reported before death as most patients with hepatic KS do not manifest symptoms or evidence of liver injury. In patients with acquired immune deficiency syndrome,...