The increased energy required for acute moderate exercise by skeletal muscle (SkM) is derived equally from enhanced fatty acid (FA) oxidation and glucose oxidation. Availability of FA also influences contracting SkM metabolic responses. Whole body glucose turnover and SkM glucose metabolic responses were determined in paired dog studies during 1) a 30-min moderate exercise (maximal oxygen consu...

Trichosanthin (TCS) is a type I ribosome--inactivating protein, which inhibits cell viability in human epithelial type 2 (HEp-2) and AMC-HN-8 human laryngeal epidermoid carcinoma cells. Although TCS is a potential chemotherapeutic agent, its mechanism of action remains to be elucidated. In the present study, HEp-2 and AMC-HN-8 cells were treated with different concentrations of TCS combined wit...

We give a representation of the volume preserving diffeomorphism of R in terms of the noncommutative (p − 2)-branes whose kinetic term is described by the Hopf term. In the static gauge, the (p − 2)brane can be described by the free fields and it suggests that the quantization of the algebra is possible. hep-th/0010040 ∗e-mail address : [email protected] †e-mail address : shibu...

Heparin and heparin partially depolymerized by enzymic digestion were separated into six size fractions. Hep 1 (tetrasaccharides), with a mean M(r) of 1200, did not release significant amounts of either lipoprotein lipase (LPL) or hepatic lipase (HL) on intravenous injection into rats. Hep 2 (mainly octa- and deca-saccharides), with a mean M(r) of 2400-3000, released both lipases. To evoke the ...

The plasma transglutaminase, factor XIIIa (FXIIIa), circulates as a zymogen containing two proteins, A and B, arranged in a noncovalent tetrameric complex, A2B2. Biosynthesis of plasma FXIII has not previously been demonstrated. In the present study, direct evidence has been obtained that two human hepatoma cell lines, Hep G2 and PLC/PRF/5, synthesize and secrete FXIII B protein. Secretion of t...

If the low energy cross section for He + p → He + e + νe, the ‘hep’ reaction, is ∼ > 20 times larger than the best (but uncertain) theoretical estimates, then this reaction could significantly influence the electron energy spectrum produced by solar neutrino interactions and measured in the SuperKamiokande, SNO, and ICARUS experiments. We compare predicted energy spectra for different assumed h...

Following the program, proposed in hep-th/0310113, of systematizing known properties of matrix model partition functions (defined as solutions to the Virasoro-like sets of linear differential equations), we proceed to consideration of non-Gaussian phases of the Hermitean one-matrix model. A unified approach is proposed for description of “connected correlators” in the form of the phaseindepende...

We develop the formalism discussed previously in hep-ph/0601209 and hep-ph/0605246 to construct a kinetic theory that provides insight into the earliest “Glasma” stage of a high energy heavy ion collision. Particles produced from the decay of classical fields in the Glasma obey a Boltzmann equation whose novel features include an inhomogeneous source term and new contributions to the collision ...

Farnesoid X receptor (FXR) belongs to the nuclear receptor superfamily with its endogenous ligands bile acids. Mice with whole body FXR deficiency develop liver tumors spontaneously, but the underlying mechanism is unclear. Moreover, it is unknown whether FXR deficiency in liver alone serves as a tumor initiator or promoter during liver carcinogenesis. This study aims to evaluate the effects of...