Maintaining appropriate surgical hemostasis is an important component of sound surgical technique and reduces postoperative morbidity and mortality. Intraoperative hemostasis can be achieved by using multiple techniques and hemostatic agents. Factors that must be considered when deciding on an appropriate hemostatic agent include tissue type, characterization of hemorrhage, vessel diameter, and...

Welcome to a very special issue of Seminars in Thrombosis and Hemostasis. This issue marks the end of another year and also represents the last issue of Seminars in Thrombosis and Hemostasis to carry the name of the founding editor, Eberhard F. Mammen, as the editor in chief. As recently announced in a previous issue of Seminars in Thrombosis and Hemostasis, Eberhard passed away on July 1 of th...

1Thrombosis and Hemostasis Unit, Ospedale Niguarda, Milan, Italy; 2Arthur Bloom Haemophilia Centre, University Hospital of Wales, School of Medicine, Cardiff University, Cardiff, United Kingdom; 3SRH Kurpfalzkrankenhaus Heidelberg GmbH and Hemophilia Center, Heidelberg, Germany; 4Department of Internal Medicine, Rouen University Hospital, Rouen Cedex, France; 5Unidad de Hemostasia y Trombosis, ...

Background: Tonsillectomy is a commonly performed surgical procedure. There are several operative methods but the superiority of one over the other has not been clearly demonstrated. The aim of this study was to compare the morbidity associated with tonsillectomy using two different techniques for hemostasis – silk ligation versus diathermy. Material and Methods: This was an experimental study ...

BACKGROUND Cardiac interventions are widely accepted as a practical treatment option for coronary artery disease. However, few changes have occurred in the techniques used for percutaneous arterial cannulation and for attaining hemostasis after cardiac interventions. To date, researchers have focused on techniques to achieve optimal hemostasis at the time of removal of the arterial catheter and...

The current understanding of hemostasis is focused on the cell-based model, which gives a more physiologic representation of blood clotting compared to the traditional cascade model. It consists of initiation, amplification and propagation phases. Initiation occurs when injury allows cells bearing tissue factor (Factor III) to react with Factor VII, ultimately resulting in the generation of a s...

Abstract Hemorrhage is the phenomenon of blood loss caused by vascular trauma or other pathological reasons, which life-threatening in severe cases. Because microhemorrhage difficult to visually monitor and pre-treat vivo , it necessary establish vitro prediction methods study hemostasis mechanism different physiological environments. In this study, a microfluidic bleeding model was developed i...

Introduction: In the treatment of hepatic injuries, there is not always adequate and secure hemostasis. A hepatic biopsy is indispensable in the evolution of focal or diffuse liver cell disease, being necessary for candidates for liver transplant and post-transplant treatment. Many patients suffer blood clotting that increases the risk of bleeding. For this reason, it is necessary to seek for s...

This chapter will discuss coagulation in the context of a hemostatic response to a break in the vasculature. Coagulation is the process that leads to fibrin formation; this process involves controlled interactions between protein coagulation factors. Hemostasis is coagulation that occurs in a physiological (as opposed to pathological) setting and results in sealing a break in the vasculature. T...

BACKGROUND/OBJECTIVES In endoscopic retrograde cholangiopancreatography, post-sphincterotomy bleeding (PSB) is a common complication of biliary sphincterotomy. Recently, the temporary placement of fully-covered metal stents (FCMS) into the biliary tree in order to achieve a tamponade effect has been described as an additional therapeutic option for PSB. The aim of this article is to review the ...