To fully understand brain function, one must look beyond the level of a single neuron. By elucidating the spatial properties of the columnar and laminar functional architectures, information regarding the neural processing in the brain can be gained. To map these fine functional structures noninvasively and repeatedly, functional magnetic resonance imaging (fMRI) can be employed. In this articl...

BACKGROUND AND OBJECTIVES The success of renal transplantation (Tx) depends on the type of donor, length of cold ischemia, and hemodynamic parameters on reperfusion. The objective of this study was to analyze the anesthetic technique, the incidence of cardiovascular changes, and the presence of postoperative diuresis of Tx performed at UNICAMP. METHODS Renal transplantation of adults performe...

BACKGROUND Qualitative and quantitative flow hemodynamic indexes have been shown to reflect right ventricular (RV) afterload and function in pulmonary hypertension (PH). We aimed to quantify flow hemodynamic formations in pulmonary arteries using 4-dimensional flow cardiac magnetic resonance imaging and the spatial velocity derivatives helicity and vorticity in a heterogeneous PH population. ...

OBJECTIVE Assess outcome in children treated with inotrope, vasopressor, and/or vasodilator therapy for reversal of fluid-refractory and persistent septic shock. DESIGN Survey; case series. SETTING Three pediatric hospitals. PATIENTS Fifty consecutive patients with fluid-refractory septic shock with a pulmonary artery catheter within 6 hours of resuscitation. INTERVENTIONS Patients were...

OBJECTIVE To assess the effect of cilazapril treatment on several hemodynamic parameters during handgrip maneuvers in patients with congestive heart failure. Cilazapril, an ACE inhibitor with high affinity, has been shown to be highly effective against a variety of vascular disorders. The effectiveness of isometric handgrip exercise on changes of cardiovascular hemodynamic parameters before and...

We evaluated the hemodynamic effects of isometric exercise in 53 patients with congestive heart failure (CHF) and compared them with those found in 10 normal subjects. In both groups, isometric exercise increased heart rate and blood pressure. Systemic resistance increased in patients with CHF (1862 + 520 vs 2126 ± 642 dyne-sec-cm-5; p < .001) but not in normal subjects (1359 + 268 vs 1380 ± 25...

OBJECTIVE Chemoreceptors play an important role in the autonomic modulation of circulatory and ventilatory responses to changes in arterial O(2) and/or CO(2). However, studies evaluating hemodynamic responses to hypoxia and hypercapnia in rats have shown inconsistent results. Our aim was to evaluate hemodynamic and respiratory responses to different levels of hypoxia and hypercapnia in consciou...

To correctly interpret the results of functional neuroimaging studies in stroke, it is essential to understand how cerebrovascular disease influences hemodynamic response during neural activation. To investigate the effect of internal carotid artery (ICA) occlusive disease on the pattern of cerebral blood flow (CBF) response during visual stimulation, we used positron emission tomography to stu...

Introduction: Vascular reactivity and resting cerebral blood flow (CBF) levels lead to inter-subject variability in functional magnetic resonance imaging (fMRI) studies using the Blood Oxygen Level Dependent (BOLD) contrast to a neural task. This variability is exacerbated in an aging population [1]. Hemodynamic scaling using Resting State Fluctuation Amplitude (RSFA) or Breath hold (BH) can mi...