REVIEWER COMMENTS. These findings further support the role of environmental factors in the development of allergic disease. Limitations of this study, however, include selfreport of allergic disease without clinical verification. The majority of the participants currently reside in a metropolitan area, and it is unknown what proportion of foreignborn familiesmoved from a developing country (com...

Canids are reservoir for some zoonoses helminthic disease. They are one of main public health problem. Theaim of this study was to ascertain frequency of gastrointestinal helminthic infection of stray dogs in Zabol city,southeaster of Iran. In this descriptive study, 30 stray dogs were euthanized, intestine was removed by necropsy.Then, the intestines was opened by scalpel and their contents pa...

The indirect fluorescent antibody test has been used to detect Toxocara antibodies quantitatively in human sera. The results obtained correlate well with those obtained with the toxocara skin test. Cross reactions have been found with Ascaris lumbricoides and about one in five normal sera give a significant fluorescent reaction. The specificity of the test has been established by Ascaris adsorp...

Eosinophilic meningoencephalitis is based on clinical manifestations and microscopic identification of eosinophils present in cerebrospinal fluid (CSF). It is caused by a variety of helminthic infections with most common being angiostrongyliasis, gnathostomiasis, toxocariasis, cysticercosis, schistosomiasis, baylisascariasis, and paragonimiasis. Many case reports are there in which parasites ha...

Natural killer (NK)T cells are innate lymphocytes that release important amount of immunoregulatory cytokines (IFN-gamma and/or IL-4) shortly after T cell receptor engagement by (glyco)lipid antigens presented by the CD1d molecules. Through this property, NKT cells play pivotal role in many physiopathologic situations. Here, we review the current knowledge of the functions and mechanisms of act...