The alcoholic extract of Leucas aspera (ALA) was investigated for its antiulcer effect by two experimental models. A significant reduction in acid secretion and ulcer score was observed in rats after ALA treatment. The observed antiulcer effect of ALA may be due to a combination of antisecretary effect and a protective effect on gastric mucosa.

The chemical composition of the essential oil of Helichrysum italicum (Roth) Don ssp. italicum, collected in the National Park of Cilento and Diano Valley, Southern Italy, was studied by means of GC and GC/MS. Forty four compounds of 45 constituents were identified in the oil, mainly oxygenated sesquiterpenes. The essential oil was evaluated for its potential in vitro phytotoxic activity agains...

DNA topoisomerases are important targets for cancer chemotherapy. We investigated the effects of a methanolic extract of Helichrysum pamphylicum on mammalian DNA topoisomerase I via in vitro plasmid supercoil relaxation assays. The extracts manifested a considerable inhibition of the enzyme's activity in a dose-dependent manner. We also performed a HPLC analysis to identify the flavonoid conten...

The leaves of Helichrysum pedunculafum and H. longifolium are used for the treatment of wounds arising from male circumcision by the Xhosas and the Pandas of South Africa, respect ively. The an tibacterial activity of these herbs was compared by direct bioautography using Staphylococcus aureus. Extracts from the leaves of H. pedunculafum showed more activity against the bacterium than those fro...