The evolution of avian flight remains one of biology's major controversies, with a long history of functional interpretations of fossil forms given as evidence for either an arboreal or cursorial origin of flight. Despite repeated emphasis on the 'wing-stroke' as a necessary avenue of investigation for addressing the evolution of flight, no empirical data exist on wing-stroke dynamics in an exp...

A rise in intracellular sodium ion concentration ([Na+]i) was predicted by Hubbard in his "energy depletion mechanism" of heatstroke [ l ] but such rises have not been clearly shown. In this study, we have found rises in [Na+]i at elevated temperatures in isolated human squamous epithelial cells, by measuring changes in the fluorescence of a Na+-sensitive fluorophore which had been introduced i...

In undergoing this life, many people always try to do and get the best. New knowledge, experience, lesson, and everything that can improve the life will be done. However, many people sometimes feel confused to get those things. Feeling the limited of experience and sources to be better is one of the lacks to own. However, there is a very simple thing that can be done. This is what your teacher ...

We report here that when untreated mice underwent heat stress, they displayed thermoregulatory deficit (e.g., animals display hypothermia during room temperature exposure), brain (or hypothalamic) inflammation, ischemia, oxidative damage, hypothalamic-pituitary-adrenal axis impairment (e.g., decreased plasma levels of both adrenocorticotrophic hormone and corticosterone during heat stress), mul...

INTRODUCTION Heat illness has not declined in the U.S. military despite preventive measures. The increase in overweight recruits entering the U.S. military may lead to an increase in heat-related events. This study compares the risk of heat illness among U.S. Army recruits who exceeded body fat standards at accession to those who met standards. METHODS Recruits with excess body fat and qualif...

Horn players have observed that timpani strokes can interfere disruptively with their playing, especially when they are seated close to the timpani. Measuring the horn's transfer function in the bell-to-mouthpiece direction reveals that the horn behaves as an acoustic impedance matching device, capable of transmitting waves with pressure gains of at least 20 dB near horn playing resonances. Dur...

This study was divided into two complementary parts. In Part 1, we proposed a novel paddle strokes analysis based on the force signal from a 30-s all-out tethered test; and compared these results with video recordings. In Part 2, we investigated the relationship between force data from the same test with paddle stroke results from both methods. Eleven male elite slalom kayakers (Brazilian natio...

On 16 April 1768, Benjamin Franklin (1706–90), then 62 and in England, wrote a letter to his stay-at-home wife, Deborah (Franklin, née Read; 1708–74; Figure 1).1 “Amidst all the sickness and misfortunes of our friends,” he began, “what reason have you and I to bless God, that we at these years enjoy with our children so great a Share of health and so much happiness in other respects.” Franklin ...

Serial hemodynamic alterations were investigated in seven elderly patients with heat stroke. Their mean age was 72 +/- 6 years. The circulatory response to heat stroke was either hyperdynamic of hypodynamic. Two patients had increased cardiac index (4.3 and 4.4 L/min/m2), increased right atrial pressure (10 and 12 mm Hg), normal pulmonary capillary wedge pressure (10 and 12 mm Hg), and decrease...

Heat stroke is a life-threatening disease characterized clinically by central nervous system dysfunction and severe hyperthermia (core temperature rises to higher than 40 °C). The unchecked rise of body core temperature overwhelms intrinsic or extrinsic heat generation mechanism, thus overwhelms homoeostatic thermoregulation. Hyperthermia causes cellular and organ dysfunction with progressive e...