BACKGROUND Internal mammary irradiation is still an issue of great debate. Although treatment of internal mammary lymph nodes was routinely given in the majority of randomized trials, data in its value are still limited. The aim of this study is to determine the variability of position of the internal mammary lymph nodes using lymphoscintigraphy and to compare the dose of radiation that reaches...

Background: The dose-related effects of patient setup errors on bio-physical indices were evaluated for the conventional wedge (CW) and field-in-field (FIF) whole breast irradiation techniques (WBI). Materials and Methods: The treatment plans of 10 patients receiving left WBI were retrospectively selected for evaluation. The bio-physical effects of dose variations were evaluated by shifting the...

four patients were studied for intercostals nerve blockade in cholecystectomy. all of the patients were poor risks (class 4) and received premedication before the procedure. intercostals nerve blockade (icnb) of the 7th and 10th thoracic nerves on the right side was performed with lidocaine 1% plus adrenaline 5 ml. at each segment, t7-t10 (a total dose of 20 ml). ventilation was controlled usin...

BACKGROUND To investigate the feasibility of contouring the planning risk organ volume (PRV) for the heart, and to determine the probability of evaluating radiation dose to the heart using kilovoltage-cone beam computed tomography (kV-CBCT) in early-stage non-small-cell lung cancer (NSCLC) patients, who received stereotactic body radiotherapy (SBRT). MATERIALS AND METHODS Seventeen NSCLC pati...

OBJECTIVE Higher β-blocker dose and lower heart rate are associated with decreased mortality in patients with systolic heart failure (HF) and sinus rhythm. However, in the 30% of patients with HF with atrial fibrillation (AF), whether β-blocker dose or heart rate predict mortality is less clear. We assessed the association between β-blocker dose, heart rate and all-cause mortality in patients w...

BACKGROUND AND AIMS Agents having a positive inotropic effect on the heart are widely used for the treatment of heart failure. However, these agents have the side effect of altering heart rate. It has been established that peroxisome proliferator-activated receptor δ (PPARδ) is mediated in cardiac contraction, however the effect on heart rate is unknown. Thus, we used an agonist of PPARδ, GW074...

Objective(s): Due to wide range of medical applications as bactericidal agents, nanosilver particles (NSPs) are manufactured worldwide in large quantities. However, potential toxicity impacts of NSPs in humans and animals still remain poorly understood. The objective of this study was to investigate clinical observations, mortality and pathological changes in rats follow...

BACKGROUND Concentrations of soluble (s)ST2 predict prognosis in heart failure. We recently found changing doses of β-blocker (BB) may affect sST2 concentrations. It remains unclear whether sST2 concentrations identify benefit of BB therapy, however. METHODS AND RESULTS A total of 151 subjects with heart failure attributable to left ventricular systolic dysfunction were examined in this post ...