Thymic carcinoid tumors very rarely occur during childhood and are often associated with the production of adrenocorticotropic hormone (ACTH), which leads to Cushing’s syndrome. We describe a 7-year-old male patient with a thymic atypical carcinoid tumor who presented with cyclical Cushing’s syndrome. His tumor was initially overlooked on computed tomography scanning in the anterior mediastinum...

CARCINOID OF THE THYMUS IS A RARE PROBLEM A case is reported to add to only 16 previously reported. None of these 17 patients had the carcinoid syndrome. Complete surgical excision, if possible, is the treatment of choice.

An increased release of serotonin secreted by ileal NETs is thought to be the major factor causing the carcinoid syndrome. However, in acutely arising carcinoid crisis also other vasoactive factors may lead to hazardous fluctuations in blood pressure and bronchial constriction. In rare cases, systemic vasoconstriction can be observed, probably caused by catecholamines or similar acting substanc...

At operation a malignant bronchial carcinoid that had invaded the left atrium produced a carcinoid crisis in a 63 year old woman. A somatostatin infusion was required to resuscitate the heart and circulation and to allow subsequent resection of the carcinoid under cardiopulmonary bypass.

Patients with well-differentiated neuroendocrine tumours may develop carcinoid syndrome (CS), which is characterised by flushing, abdominal cramps, diarrhoea, and bronchospasms. In this scenario, long-term secretion of vasoactive substances-serotonin, tachynins, and others, may induce fibrogenic responses in local or distant tissues, leading to complications such as carcinoid heart disease (CHD...

BACKGROUND Neuroendocrine tumors (NETs) are heterogeneous neoplasms that originate from cells with a secretory function. Small bowel NETs (SB-NETs) are related to serotonin hypersecretion which causes: flushing, diarrhea, abdominal pain, bronchoconstriction and heart involvement, also known as carcinoid syndrome (CS). CS can be confused with an allergic reaction and thus should be considered as...

Carcinoid tumor is a slow-growing type of neuroendocrine tumor, originating in the enterochromaffin cells and secreting mainly serotonin. The diagnosis is based on clinical symptoms, hormone levels, radiological and nuclear imaging, and histological confirmation. The clinical symptoms are characterized by flushing, diarrhea, abdominal pain, telangiectasia and/or bronchoconstriction. However, mo...