Laryngeally echolocating bats avoid self-deafening (forward masking) by separating pulse and echo either in time using low duty cycle (LDC) echolocation, or in frequency using high duty cycle (HDC) echolocation. HDC echolocators are specialized to detect fluttering targets in cluttered environments. HDC echolocation is found only in the families Rhinolophidae and Hipposideridae in the Old World...

BACKGROUND High-dose chemotherapy (HDC) using sequential cycles of carboplatin/etoposide is curative for relapsed germ-cell tumors (GCT). However, outcomes of high-risk patients in advanced relapse remain poor. We previously developed a new HDC regimen combining infusional gemcitabine with docetaxel/melphalan/carboplatin (GemDMC), with preliminary high activity in refractory GCT. Given the high...

Hemodialysis catheters (HDC) are the commonly used vascular access for hemodialysis. Functioning is essential adequate dialysis. Dialysis catheter insertion under ultrasound guidance now standard practice and has reduced incidence of mechanical complications during insertion. However, such as tip misplacement puncture mediastinum cannot be prevented by ultrasound-guided procedures alone. We rep...

Introduction The concept of bone anchors constructed of High Density Collagen (HDC) was introduced at this meeting last year. The healing of tendon to bone in an animal model during the critical first six months was found to be equal to that produced with a standard metallic anchor. Collagen is being investigated as a material for making anchors to avoid the drawbacks of the materials in the cu...

Histamine and prostaglandins (PGs) play a variety of physiological roles as autacoids, which function in the vicinity of their sources and maintain local homeostasis in the body. They stimulate target cells by acting on their specific receptors, which are coupled to trimeric G proteins. For the precise understanding of the physiological roles of histamine and PGs, it is necessary to clarify the...

This paper describes a hierarchical distributed control (HDC) model for coordinating cooperative problem-solving among intelligent systems. The model was implemented using SOCIAL, an innovative object-oriented tool for integrating heterogeneous, distributed software systems. SOCIAL embeds applications in “wrapper” objects called Agents, which supply predefined capabilities for distributed commu...

A consensus genetic map of tetraploid cotton was constructed using six high-density maps and after the integration of a sequence-based marker redundancy check. Public cotton SSR libraries (17,343 markers) were curated for sequence redundancy using 90% as a similarity cutoff. As a result, 20% of the markers (3,410) could be considered as redundant with some other markers. The marker redundancy i...

We have found that at least seven hydrogen-deficient carbon (HdC) and R Coronae Borealis (RCB) stars, have O/O ratios close to and in some cases less than unity, values that are orders of magnitude lower than measured in other stars (the Solar value is 500). Greatly enhanced O is evident in every HdC and RCB we have measured that is cool enough to have detectable CO bands. The three HdC stars m...

BACKGROUND Data from a randomized multinational phase 3 trial of 320 adults with acute myeloid leukemia (AML) demonstrated that maintenance therapy with 3-week cycles of histamine dihydrochloride plus low-dose interleukin-2 (HDC/IL-2) for up to 18 months significantly improved leukemia-free survival (LFS) but lacked power to detect an overall survival (OS) difference. PURPOSE To assess the co...

Data from rat models for alcohol preference and histidine decarboxylase knockout (HDC KO) mice suggest that brain histamine regulates alcohol-related behaviors. Histamine levels are higher in alcohol-preferring than in alcohol-nonpreferring rat brains, and expression of histamine H(3) receptor (H(3)R) is different in key areas for addictive behavior. H(3)R inverse agonists decrease alcohol resp...