Pesticide exposure has been implicated as an environmental risk factor for the development of type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the association of the body burden of the pesticide hexachlorocyclohexane (HCH) with the risk of T2DM in a sample of adults from Saudi Arabia. Serum samples were obtained from 280 adult subjects. Hexachlorocyclohexane isomer resi...

The levels and distribution patterns of the selected organochlorine pesticides (OCPs=p,p'-DDT, o,p'-DDT, p,p'-DDE, p,p'-DDD, alpha-, beta-, gamma- and delta-HCH) in surficial sediments from the Haihe River and Dagu Drainage River of Tianjin were investigated by means of gas chromatography coupled with micro-electronic capture detector (GC-microECD). Concentrations of OCPs in the sediments from ...

A total of fifty-four human breast milk samples were collected from Pediatric Department of Assiut University Hospital from lactating mothers during January-August, 2001. The samples were analyzed for organochlorine pesticide residues by using gas chromatography-electron capture detector (GC-ECD). The results revealed that all detected organochlorine residue levels were markedly lower in compar...

In the last few decades, highly toxic organic compounds like the organochlorine pesticide (OP) hexachlorocyclohexane (HCH) have been released into the environment. All HCH isomers are acutely toxic to mammals. Although nowadays its use is restricted or completely banned in most countries, it continues posing serious environmental and health concerns. Since HCH toxicity is well known, it is impe...

Introduction The diagnosis of hypochondroplasia (HCH) is hampered by absence of radiological criteria relevant to the agedependent manifestations, particularly those in the neonatal period. This work deals with the radiological features in hypochondroplastic neonates with a FGFR3 mutation, including quantitative measurement that facilitates the definitive diagnosis. We propose the radiological ...

Bacillus subtilisstrain HUK15 has been isolated from hexachlorocyclohexane (HCH)-long-term-contaminated soil. The genome of strain HUK15 was sequenced to investigate its adaptation toward HCH and its potential capability to degrade the pesticide. Here, we report the annotated draft genome sequence (~4.3 Mbp) of this strain.

Sphingobium indicum B90A, an efficient degrader of hexachlorocyclohexane (HCH) isomers, was isolated in 1990 from sugarcane rhizosphere soil in Cuttack, India. Here we report the draft genome sequence of this bacterium, which has now become a model system for understanding the genetics, biochemistry, and physiology of HCH degradation.

Pseudomonassp. HUK17 has been isolated from hexachlorocyclohexane (HCH) long-term contaminated soil. The genome of strain HUK17 was sequenced to elucidate its adaptation toward HCH and to evaluate the presence of pesticide degradation pathways. Here, we report the annotated draft genome sequence (~2.6 Mbp) of this strain.

Air samples collected during 1994–2000 at the Canadian Arctic air monitoring station Alert (8230 N, 6220W) were analysed by enantiospecific gas chromatography–mass spectrometry for αhexachlorocyclohexane (α-HCH), trans-chlordane (TC) and cis-chlordane (CC). Results were expressed as enantiomer fractions (EF = peak areas of (+)/[(+)+ (−)] enantiomers), where EFs = 0.5, < 0.5 and > 0.5 indicate r...