context hepatitis b virus (hbv) and hepatitis c virus (hcv) infections constitute a major global health problem. about 60,000 and 350,000 deaths occur as the results of hbv and hcv infections, respectively. chronic hepatitis b and c infections are leading causes of cirrhosis and hepatocellular carcinoma (hcc) which are considered as the third cancer-associated cause of deaths worldwide. iran su...

Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the main causes of severe liver failure worldwide. This study was conducted to evaluate the incidence rate and trend of these infections over six successive years from 2008 to 2013 in Ilam Province, western Iran. Methods: We studied the registered data of HBV and HCV based on the National Notifiable Diseases Surveil...

INTRODUCTION Mutation of the HBV precore gene prevents the production of HBeAg, which is an important target for immune responses. Distribution of this mutation varies along with frequency of HBV genotypes in accordance with geographic and ethnic variations. The general objective of this study was to evaluate the prevalence and characteristics of precore mutation in Iran and its correlation wit...

The migration of refugees not only facilitates but also increases the risk of the spread of infectious diseases such as viral hepatitis. During the two last decades, because of 23 years (1978—2001) of civil war in Afghanistan, a considerable number of Afghan people have left their homeland and have migrated to neighboring countries. Iran, as Afghanistan’s western neighbor, has hosted approximat...

Childhood Hepatitis B virus (HBV) infection causes both medical and public health challenges. Infants who acquire HBV parentally have up to 90% risk of developing chronic HBV infection. It is now estimated that approximately 10% of worldwide cancers are attributable to viral infection, with the vast majority (>85 %) occurring in the developing world. In this distribution, elevated rate and prev...

AIM The aim of this study was to determine the prevalence of HDV infection between HBV chronic patients referred to gastroenterology ward of Taleghani hospital Tehran, Iran and also investigating the risk factors in acquiring the HDV infection. BACKGROUND Hepatitis B virus (HBV) and Hepatitis D virus (HDV) are major public health issues. Worldwide there are approximately 350 million individua...

Injection drug use has been the most growing rout of drug abuse in Iran in the past decade and it has been responsible for the transmission of HIV virus in more than two third of cases. The aim of the present study was to determine the prevalence of HIV and hepatitis B in a group of IDU cadavers and to compare the results to a group of cadavers of the normal population. In a case-control study ...

Mohammadali F, Pourfathollah AA. Changes in frequency of HBV, HCV, HIV and syphilis infections among blood donors in Tehran province 2005 2011. Arch Iran Med 2014; 17(9)613-620 The routine screening of blood donors for potentially transmissible infections has reduced transfusion-associated infection whilst providing an insight into disease prevalence. This retrospective cross-sectional study ev...

OBJECTIVE To identify the distribution pattern of Hepatitis B Virus (HBV) genotype in a group of patients and to study its phylogenetic divergence. STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY The clinics of Gastroenterology Unit, Ziauddin University, from January to December 2006. METHODOLOGY Two hundred and one HBV infected patients were genotyped for this study. All...

Hepatitis B is one of the most frequent post-transfusion infections. Occult hepatitis B infection (OBI) is a form of hepatitis B infection in which, despite the presence of HBV-DNA in the serum and hepatocytes of the carrier, HBsAg is absent. In addition to the risk of transmission through the transfusion of infected blood, reactivation of hepatitis B in OBI patients and recipients of their blo...