abstract mutations have been described in all of the four open reading frames of the hepatitis b virus (hbv), however, from a clinical perspective the surface escape mutant is the most troublesome. hepatitis b surface antigen (hbsag) variants may impair diagnosis, or allow the virus to escape vaccine-induced immunity or passive immunoglobulin therapy. hbv mutants with amino acid substitutions, ...

conclusions in our study, only hbv genotype d was found among all the positive hbsag and occult hbv infection. moreover, high prevalence (40.7%) of occult hbv infection was determined among patients suffered from cryptogenic cirrhosis. results eleven (40.7%) out of 27 hbv cryptogenic cirrhosis and all 11 hbsag-positive patients were positive for hbv dna. the seroprevalences of hepatitis b virus...

Abstract Background and Aims Patients with end-stage renal disease (ESRD) frequently present serologic evidence of previous contact hepatitis B virus (HBV). Although uncommon, HBV reactivation after kidney transplantation (KT) may cause serious complications adverse outcomes in these patients. However, data regarding risk factors for are still scarce. This study aims to describe a cohort patien...

BACKGROUND Diagnosis and control programs for infectious diseases among immigrants are the most important aspects of epidemiological studies for both origin and destination countries. Data about hepatitis B virus (HBV) infection among the Afghan immigrants in Iran is limited. OBJECTIVES To the best of HBV treatment and prevention in Afghan immigrants in Iran, the present study was conducted t...

The detection and quantification of hepatitis B virus (HBV) DNA are essential for the diagnosis and treatment of chronic HBV infection. The use of real-time PCR assays for HBV DNA quantification is strongly recommended. The goal of this study was to evaluate the intrinsic characteristics and clinical performance of version 2.0 (v2.0) of the Cobas AmpliPrep/Cobas TaqMan (CAP/CTM) assay, a fully ...

evidence has shown that liver disease caused by hepatitis viruses can be more aggressive and severe in hiv infected subjects. therefore, the present cross-sectional study aimed to evaluate the seroprevalence of hdv infection among hiv/hbv co-infected clients in shiraz, southwest iran. in this study, 178 patients co-infected with hbv and hiv individuals were enrolled. the diagnosis of hiv infect...

BACKGROUND The risk of Hepatitis B virus (HBV) reactivation in patients with different hematological malignancy except lymphoma were rarely known before. METHODS A total of 1962 patients with hematological malignancy were enrolled and followed-up at the National Taiwan University Hospital between 2008 and 2013. The clinical characteristics, HBV serology, and laboratory data were retrospective...

A 58-year-old man was diagnosed as a hepatitis B virus (HBV) carrier approximately 30 years ago. He was diagnosed with renal cell carcinoma when he was 57 years old. Radical nephrectomy was performed, and everolimus was administered to treat his lung metastasis. After beginning the everolimus, intermittent fever, general fatigue, and jaundice developed. He was admitted under a diagnosis of flar...

Hepatitis viruses (HAV, HBV, HCV, HDV and HEV) are attributed to a wide spectrum of acute and chronic liver diseases, including carcinomas. Worldwide, >250 million become chronically infected by HBV and ~150 million by HCV every year. Though, new hepatotropic viruses, such as HGV, GBV, TTV and SENV are identified in chronic liver diseases, thousands still suffer of unknown etiology. Despite a p...