The present study focuses on effects of initial pH on dibenzothiophene (DBT) desulfurization via 4S pathway by growing cells of Ralstonia eutropha. For so doing, temporal changes of biomass concentration, glucose as a sole carbon source, pH value, and 2-hydroxybiphenyl (2-HBP) formation have been monitored during the bioprocess. The biomass concentration has been modeled by the logistic equatio...

The present study focuses on effects of initial pH on dibenzothiophene (DBT) desulfurization via 4S pathway by growing cells of Ralstonia eutropha. For so doing, temporal changes of biomass concentration, glucose as a sole carbon source, pH value, and 2-hydroxybiphenyl (2-HBP) formation have been monitored during the bioprocess. The biomass concentration has been modeled by the logistic equatio...

Introduction: We compared in a prospective open-label study two different protocols of home self-measurement of arterial blood pressure (ABP) for the detection of antiangiogenic drugs (AAG)-induced arterial hypertension (AHT). Material and methods: We performed 3 measurements every morning and evenings measurements for 3 successive days (hBP-3d) and compared them to a single daily morning measu...

Decreased hepatic function in patients with hepatoma or liver metastasis monitored by a hepatocyte specific galactosylated radioligand Summary 9'Tc-galactosylated neoglycoalbumin ("mTc-NGA) is a hepatocyte-specific tracer that, after injection into the blood stream, delivers radioactivity selectively to the liver. This is based upon chemical recognition and binding by the hepatic binding protei...

We previously identified a five-member family of hemin-binding proteins (Hbp's) of Bartonella quintana that bind hemin on the outer surface but share no homology with known bacterial heme receptors. Subsequently, we demonstrated that expression of the hbp family is significantly influenced by oxygen, heme, and temperature conditions encountered by the pathogen in the human host and the body lou...

Glycolysis is a process that rapidly converts glucose to lactate to produce adenosine triphosphate (ATP) under anaerobic conditions and occurs in all eukaryotic and prokaryotic cells. On the other hand, the hexosamine biosynthetic pathway (HBP) converts glucose to intermediate products like UDP-N-acetylglucosamine, which is critical for post-translational modifications of proteins, such as prot...

RNA interference (RNAi), a gene silencing process, has been recently exploited to determine gene function by degrading specific mRNAs in several eukaryotic organisms. We constructed a double stranded RNA (dsRNA) from a previously cloned putative Amblyomma americanum histamine binding protein (HBP) to test the significance of using this methodology in the assessment of the function and importanc...

BACKGROUND This study investigated the prevalence of chemotherapy-induced nausea and vomiting (CINV) in patients with hepatobiliary-pancreatic (HBP) cancer in a prospective nationwide survey. PATIENTS AND METHODS One hundred patients with HBP cancer (biliary tract cancer; n=70, hepatocellular carcinoma; n=20, and pancreatic cancer; n=10) who received chemotherapy for the first time were analy...

Decoding the human brain is perhaps the most fascinating scientific challenge in the 21st century. The Human Brain Project (HBP), a 10-year European Flagship, targets the reconstruction of the brain's multi-scale organization. It uses productive loops of experiments, medical, data, data analytics, and simulation on all levels that will eventually bridge the scales. The HBP IT architecture is un...

The inhibitor), effect of hop bract polyphenols (HBP) on cariogenic streptococci was investigated. It wu'as fbund that the high molecular weight polyphenol (estimated about 36,OeO-40,OOO) inhibited the cellular adherence of Streptoeoccus mutans MT8148 (serotype C) and Streptoeoeeus sobrinus ATCC 33478 (serotype g) at msuch smaller concentrations than the polyphenols extracted from oe)ong tea or...